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Testing Data

IL-7 active protein

Murine IL-7

Gene Names
Il7; Il-7; hlb368; A630026I06Rik
Reactivity
Species Reactivity: Mouse
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
IL-7; Murine IL-7; Recombinant Murine IL-7; IL-7 active protein
Ordering
For Research Use Only!
Host
E Coli
Reactivity
Species Reactivity: Mouse
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
MECHIKDKE GKAYESVLM ISIDELDKM TGTDSNCPN NEPNFFRKH VCDDTKEAA FLNRAARKL KQFLKMNIS EEFNVHLLT VSQGTQTLV NCTSKEEKN VKEQKKNDA CFLKRLLRE IKTCWNKIL KGSI
Biological Activity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is <= 0.2 ng/ml, corresponding to a specific activity of >= 5 x 106 units/mg.
Cell Type
B Cells, T Cells, Stem Cells
Preparation and Storage
At -20 degree C

Testing Data

Testing Data
Related Product Information for IL-7 active protein
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Product Categories/Family for IL-7 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
17,727 Da
NCBI Official Full Name
Interleukin-7
NCBI Official Synonym Full Names
interleukin 7
NCBI Official Symbol
Il7
NCBI Official Synonym Symbols
Il-7; hlb368; A630026I06Rik
NCBI Protein Information
interleukin-7
UniProt Protein Name
Interleukin-7
UniProt Gene Name
Il7
UniProt Synonym Gene Names
Il-7; IL-7
UniProt Entry Name
IL7_MOUSE

NCBI Description

The protein encoded by this gene is a hematopoietic growth factor important for B and T cell development. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]

Uniprot Description

IL7: Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytokine; Cell cycle regulation; Cell development/differentiation; Apoptosis; Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: interleukin-7 receptor binding; growth factor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity

Biological Process: T cell lineage commitment; organ morphogenesis; cell-cell signaling; positive regulation of T cell differentiation; homeostasis of number of cells within a tissue; regulation of gene expression; negative regulation of catalytic activity; positive regulation of B cell proliferation; immune response; positive regulation of organ growth; humoral immune response; bone resorption

Research Articles on IL-7

Similar Products

Product Notes

The IL-7 il7 (Catalog #AAA695721) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine IL-7 reacts with Species Reactivity: Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MECHIKDKE GKAYESVLM ISIDELDKM TGTDSNCPN NEPNFFRKH VCDDTKEAA FLNRAARKL KQFLKMNIS EEFNVHLLT VSQGTQTLV NCTSKEEKN VKEQKKNDA CFLKRLLRE IKTCWNKIL KGSI. It is sometimes possible for the material contained within the vial of "IL-7, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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