Cardiotrophin-1 Active Protein | Ctf1 active protein
Mouse Cardiotrophin-1
Gene Names
Ctf1; CT-1
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC
Synonyms
Cardiotrophin-1; Mouse Cardiotrophin-1; Recombinant Murine Cardiotrophin-1; Ctf1 active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC
Form/Format
Lyophilized
Sequence
SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEE YVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA A ALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVET VLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LY GEWVSRTE GDLGQLVPGG VA
Sequence Length
203
Endotoxin Level
< 0.1 ng per ug of Cardiotrophin-1
Biological Activity
The ED50 as determined by the dose-dependent proliferation of TF-1 cells was <= 1.0 ng/ml, corresponding to a specific activity of >= 1 x 106 units/mg.
Related Product Information for Ctf1 active protein
CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NNT-1/BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.
Product Categories/Family for Ctf1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
21.3 kDa
NCBI Official Full Name
cardiotrophin-1
NCBI Official Synonym Full Names
cardiotrophin 1
NCBI Official Symbol
Ctf1
NCBI Official Synonym Symbols
CT-1
NCBI Protein Information
cardiotrophin-1
UniProt Protein Name
Cardiotrophin-1
Protein Family
UniProt Gene Name
Ctf1
UniProt Synonym Gene Names
CT-1
UniProt Entry Name
CTF1_MOUSE
Uniprot Description
Function: Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
Subcellular location: Secreted.
Tissue specificity: Highly expressed in heart, skeletal muscle, liver, lung and kidney. Lower levels in testis and brain. No expression in spleen.
Sequence similarities: Belongs to the IL-6 superfamily.
Research Articles on Ctf1
Similar Products
Product Notes
The Ctf1 ctf1 (Catalog #AAA692090) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse Cardiotrophin-1 reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: SQREGSLEDH QTDSSISFLP HLEAKIRQTH NLARLLTKYA EQLLEE YVQQ QGEPFGLPGF SPPRLPLAGL SGPAPSHAGL PVSERLRQDA An ALSVLPALL DAVRRRQAEL NPRAPRLLRS LEDAARQVRA LGAAVET VLA ALGAAARGPG PEPVTVATLF TANSTAGIFS AKVLGFHVCG LY GEWVSRTE GDLGQLVPGG VA. It is sometimes possible for the material contained within the vial of "Cardiotrophin-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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