BCA-1 active protein
Mouse BCA-1
Gene Names
Cxcl13; BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
Reactivity
Mouse
Purity
> 98% by SDS-PAGE and HPLC
Synonyms
BCA-1; Mouse BCA-1; Recombinant Murine BCA-1/BCL; BCA-1 active protein
Host
E Coli
Reactivity
Mouse
Purity/Purification
> 98% by SDS-PAGE and HPLC
Form/Format
Lyophilized
Sequence
VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVW KKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
Sequence Length
109
Endotoxin Level
< 0.1 ng per ug of BCA-1/BCL
Biological Activity
Determined by its ability to chemoattract human B cells using a concentration range of 1.0-10.0 ng/ml.
Related Product Information for BCA-1 active protein
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant murine BLC is a 9.8 kDa protein containing 88 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
Product Categories/Family for BCA-1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
9.8 kDa
NCBI Official Full Name
C-X-C motif chemokine 13
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 13
NCBI Official Symbol
Cxcl13
NCBI Official Synonym Symbols
BLC; Angie; BCA-1; BLR1L; ANGIE2; Scyb13; 4631412M08Rik
NCBI Protein Information
C-X-C motif chemokine 13; CXC chemokine BLC; B lymphocyte chemoattractant; small-inducible cytokine B13; small inducible cytokine subfamily B (Cys-X-Cys), member 13
UniProt Protein Name
C-X-C motif chemokine 13
Protein Family
UniProt Gene Name
Cxcl13
UniProt Synonym Gene Names
Blc; Scyb13
UniProt Entry Name
CXL13_MOUSE
Uniprot Description
Function: Strongly chemotactic for B-lymphocytes, weakly for spleen monocytes and macrophages but no chemotactic activity for granulocytes. Binds to BLR1/CXCR5. May play a role in directing the migration of B-lymphocytes to follicles in secondary lymphoid organs.
Subcellular location: Secreted.
Tissue specificity: Found in spleen (B-cell-rich zone or follicles), Peyer patches (strongest within germinal centers and extending to the mantle zone) and lymph nodes (in reticular pattern in follicles).
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Research Articles on BCA-1
Similar Products
Product Notes
The BCA-1 cxcl13 (Catalog #AAA692003) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Mouse BCA-1 reacts with Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVW KKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP. It is sometimes possible for the material contained within the vial of "BCA-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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