Interleukin-3 Active Protein | mIL 3 active protein
Recombinant Mouse Interleukin-3
Sterile Filtered White lyophilized (freeze-dried) powder.
Introduction: Interleukin-3 is a pleiotropic cytokine produced primarily by activated T cells. IL-3 is thought to function via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines. IL-3 has also been shown to affect the functional activity of a variety of other cell types including mast cells, eosinophils, megakaryocytes and basophils.
NCBI and Uniprot Product Information
Uniprot Description
IL3: Granulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. Belongs to the IL-3 family.
Protein type: Cytokine; Cell cycle regulation; Secreted; Oncoprotein; Secreted, signal peptide; Apoptosis
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-3 receptor binding; growth factor activity; cytokine activity
Biological Process: regulation of protein amino acid dephosphorylation; myeloid cell apoptosis; negative regulation of autophagy; cytokine and chemokine mediated signaling pathway; response to hormone stimulus; positive regulation of JNK cascade; positive regulation of peptidyl-tyrosine phosphorylation; negative regulation of mast cell apoptosis; regulation of gene expression; regulation of glycolysis; positive regulation of cell proliferation; response to hypoxia; hemopoiesis; immune response; regulation of cell growth; positive regulation of myeloid leukocyte differentiation; positive regulation of protein amino acid phosphorylation; negative regulation of apoptosis
Research Articles on mIL 3
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Product Notes
The mIL 3 il3 (Catalog #AAA142248) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Asp-Th r-His-Arg. It is sometimes possible for the material contained within the vial of "Interleukin-3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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