Interleukin 1 Family Active Protein | IL1F10 active protein
Recombinant Human Interleukin 1 Family, Member 10
Gene Names
IL1F10; IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Interleukin 1 Family; Recombinant Human Interleukin 1 Family; Member 10; IL1F10 Human; Member 10 Human Recombinant; Interleukin-1 family member 10; IL-1F10; FIL1 theta; Interleukin-1 HY2; IL-1HY2; Interleukin-1 theta; IL-1 theta; IL1F10; FIL1T; IL1HY2; FKSG75; MGC119831; MGC119832; MGC119833; FIL1-theta; IL1F10 active protein
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
IL1F10 was lyophilized after extensive dialysis against 20mM Phosphate buffer, pH7.4.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sterile Filtered White lyophilized (freeze-dried) powder.
Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Cys-Ser-Leu-Pro
Sequence Length
152
Solubility
It is recommended to quick spin followed by reconstitution of IL1F10 in PBS to a concentration no less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
Biological Activity
As measured by its binding ability in a functional ELISA, immobilized IL1F10 at 1 ug/ml (100 ul/well) can bind rHuIL-1 Rrp2/Fc Chimera with a linear range of 0.15- 5 ug/ml.
Preparation and Storage
Lyophilized IL1F10 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL1F10 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
Related Product Information for IL1F10 active protein
Description: IL1F10 Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 152 amino acids and having a molecular mass of 17kDa.The IL1F10 is purified by proprietary chromatographic techniques.
Introduction: Human interleukin family 1, member 10 (IL1F10) belongs to the interleukin 1 cytokine family. IL1F10 is expressed in the fetal skin, spleen and tonsil, generally in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL1F10 binds soluble IL1 receptor type 1 and may be implicated in the regulation of adapted and innate immune responses.
Introduction: Human interleukin family 1, member 10 (IL1F10) belongs to the interleukin 1 cytokine family. IL1F10 is expressed in the fetal skin, spleen and tonsil, generally in the basal epithelia of skin and in proliferating B-cells of the tonsil. IL1F10 binds soluble IL1 receptor type 1 and may be implicated in the regulation of adapted and innate immune responses.
Product Categories/Family for IL1F10 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16,701 Da
NCBI Official Full Name
interleukin-1 family member 10
NCBI Official Synonym Full Names
interleukin 1 family, member 10 (theta)
NCBI Official Symbol
IL1F10
NCBI Official Synonym Symbols
IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta
NCBI Protein Information
interleukin-1 family member 10; FIL1 theta; IL-1 theta; IL-1F10 (canonical form IL-1F10a); family of interleukin 1-theta; interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; interleukin-38
UniProt Protein Name
Interleukin-1 family member 10
Protein Family
UniProt Gene Name
IL1F10
UniProt Synonym Gene Names
FIL1T; IL1HY2; IL38; IL-1F10; FIL1 theta; IL-1HY2; IL-1 theta; IL-38
UniProt Entry Name
IL1FA_HUMAN
NCBI Description
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
Uniprot Description
IL1F10: Binds soluble IL-1 receptor type 1. Belongs to the IL-1 family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Cytokine
Chromosomal Location of Human Ortholog: 2q13
Cellular Component: extracellular space
Molecular Function: interleukin-1 receptor binding; cytokine activity
Biological Process: cytokine and chemokine mediated signaling pathway
Research Articles on IL1F10
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Product Notes
The IL1F10 il1f10 (Catalog #AAA144603) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence of the first five N-terminal amino acids was determined and was found to be Met-Cys-Se r-Leu-Pro. It is sometimes possible for the material contained within the vial of "Interleukin 1 Family, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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