Testing Data
IL-22 Active Protein | IL -22 active protein
Human IL-22
Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
Reactivity
Species Reactivity: Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
IL-22; Human IL-22; Recombinant Human IL -22; IL -22 active protein
Host
E Coli
Reactivity
Species Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
MAPISSHCR LDKSNFQQP YITNRTFML AKEASLADN NTDVRLIGE KLFHGVSMS ERCYLMKQV LNFTLEEVL FPQSDRFQP YMQEVVPFL ARLSNRLST CHIEGDDLH IQRNVQKLK DTVKKLGES GEIKAIGEL DLLFMSLRN ACI
Biological Activity
Assay #1: Determined by its ability to activate STAT following receptor ligand interaction. Assay #2: Measured by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The expected ED
Cell Type
T Cells
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for IL -22 active protein
IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-beta/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.
Product Categories/Family for IL -22 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,011 Da
NCBI Official Full Name
Interleukin-22
NCBI Official Synonym Full Names
interleukin 22
NCBI Official Symbol
IL22
NCBI Official Synonym Symbols
TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; TIFIL-23
NCBI Protein Information
interleukin-22; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor
UniProt Protein Name
Interleukin-22
UniProt Gene Name
IL22
UniProt Synonym Gene Names
ILTIF; ZCYTO18; IL-22; IL-TIF
UniProt Entry Name
IL22_HUMAN
Uniprot Description
IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.
Protein type: Secreted, signal peptide; Cytokine; Secreted
Chromosomal Location of Human Ortholog: 12q15
Cellular Component: extracellular space; extracellular region
Molecular Function: interleukin-22 receptor binding; cytokine activity
Biological Process: cell-cell signaling; response to glucocorticoid stimulus; acute-phase response; inflammatory response
Research Articles on IL -22
Similar Products
Product Notes
The IL -22 il22 (Catalog #AAA696069) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human IL-22 reacts with Species Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MAPISSHCR LDKSNFQQP YITNRTFML AKEASLADN NTDVRLIGE KLFHGVSMS ERCYLMKQV LNFTLEEVL FPQSDRFQP YMQEVVPFL ARLSNRLST CHIEGDDLH IQRNVQKLK DTVKKLGES GEIKAIGEL DLLFMSLRN ACI. It is sometimes possible for the material contained within the vial of "IL-22, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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