OTOR (Otoraplin) Active Protein | OTOR active protein
Human OTOR (Otoraplin)
Gene Names
OTOR; FDP; MIAL1
Reactivity
Human
Purity
98 % (SDS-PAGE, HPLC)
Synonyms
OTOR (Otoraplin); Human OTOR (Otoraplin); Recombinant Human OTOR; OTOR active protein
Host
E Coli
Reactivity
Human
Purity/Purification
98 % (SDS-PAGE, HPLC)
Form/Format
Lyophilized
Sequence
MVHGIFMDRL ASKKLCADDE CVYTISLASA QEDYNAPDCR FINVKK GQQI YVYSKLVKEN GAGEFWAGSV YGDGQDEMGV VGYFPRNLVK E QRVYQEATK EVPTTDIDFF CE
Sequence Length
128
Endotoxin Level
< 0.1 ng per ug of OTOR
Biological Activity
Data not available.
Related Product Information for OTOR active protein
OTOR, also called Otoraplin and MIAL, is a secreted cytokine and a member of the MIA/OTOR family. Members of this family which also includes MIA, MIA2, and TANGO share a Src homology-3 (SH3)-like domain. OTOR is predominantly expressed in the cochlea of the inner-ear and to a lesser extent in fetal brain and in some cartilage tissues. OTOR appears to be involved in early chondrogenesis of the otic capsule, which is required for normal inner ear development and auditory function. Recombinant human OTOR is a 12.7 kDa globular protein containing 112 amino acid residues.
Product Categories/Family for OTOR active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
12.7 kDa
NCBI Official Full Name
otoraplin
NCBI Official Synonym Full Names
otoraplin
NCBI Official Symbol
OTOR
NCBI Official Synonym Symbols
FDP; MIAL1
NCBI Protein Information
otoraplin; fibrocyte-derived protein; melanoma inhibitory activity-like protein
UniProt Protein Name
Otoraplin
Protein Family
UniProt Gene Name
OTOR
UniProt Synonym Gene Names
FDP; MIAL
UniProt Entry Name
OTOR_HUMAN
NCBI Description
This gene encodes a member of the melanoma-inhibiting activity gene family. The encoded protein is secreted via the Golgi apparatus and may function in cartilage development and maintenance. A frequent polymorphism in the translation start codon of this gene can abolish translation and may be associated with forms of deafness. [provided by RefSeq, Jul 2013]
Uniprot Description
Subcellular location: Secreted
Potential.
Tissue specificity: Highly expressed in cochlea.
Sequence similarities: Belongs to the MIA/OTOR family.Contains 1 SH3 domain.
Research Articles on OTOR
Similar Products
Product Notes
The OTOR otor (Catalog #AAA691657) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human OTOR (Otoraplin) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MVHGIFMDRL ASKKLCADDE CVYTISLASA QEDYNAPDCR FINVKK GQQI YVYSKLVKEN GAGEFWAGSV YGDGQDEMGV VGYFPRNLVK E QRVYQEATK EVPTTDIDFF CE. It is sometimes possible for the material contained within the vial of "OTOR (Otoraplin), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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