NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with a suggested role in calcium level maintenance, eating regulation in the hypothalamus, and release of tumor necrosis factor from vascular endothelial cells. This protein binds calcium and has EF-folding domains. [provided by RefSeq, Oct 2011]
Uniprot Description
NUCB2: Calcium-binding protein. May have a role in calcium homeostasis. Belongs to the nucleobindin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle; Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 11p15.1
Cellular Component: Golgi apparatus; extracellular space; endoplasmic reticulum; ER-Golgi intermediate compartment; plasma membrane; nuclear envelope; cytosol
Molecular Function: protein binding; DNA binding; calcium ion binding
Research Articles on NUCB2
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Product Notes
The NUCB2 nucb2 (Catalog #AAA695907) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Nesfatin-1 reacts with Species Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: VPIDIDKTK VQNIHPVES AKIEPPDTG LYYDEYLKQ VIDVLETDK HFREKLQKA DIEEIKSGR LSKELDLVS HHVRTKLDE L. It is sometimes possible for the material contained within the vial of "Nesfatin-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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