Myostatin-Propeptide Active Protein | MSTN active protein
Human Myostatin-Propeptide
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Acts specifically as a negative regulator of skeletal muscle growth.
Subunit structure: Homodimer; disulfide-linked
By similarity. Interacts with WFIKKN2, leading to inhibit its activity. Interacts with FST3. Ref.5 Ref.7
Subcellular location: Secreted.
Involvement in disease: Muscle hypertrophy (MSLHP) [MIM:614160]: A condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.6
Sequence similarities: Belongs to the TGF-beta family.
Research Articles on MSTN
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Product Notes
The MSTN mstn (Catalog #AAA691687) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human Myostatin-Propeptide reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLET APNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH A TTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIY LRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQ SIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLN PF LEVKVTDTPK RSRR. It is sometimes possible for the material contained within the vial of "Myostatin-Propeptide, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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