GCP-2 (CXCL6) active protein
Human GCP-2 (CXCL6)
Gene Names
CXCL6; GCP2; CKA-3; GCP-2; SCYB6
Reactivity
Human
Purity
> 98% by SDS-PAGE and HPLC analyses
Synonyms
GCP-2 (CXCL6); Human GCP-2 (CXCL6); Recombinant Human GCP-2; GCP-2 (CXCL6) active protein
Host
E Coli
Reactivity
Human
Purity/Purification
> 98% by SDS-PAGE and HPLC analyses
Form/Format
Lyophilized
Sequence
VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGK QVCL DPEAPFLKKV IQKILDSGNK KN
Sequence Length
21
Endotoxin Level
< 0.1 ng per g of GCP-2
Biological Activity
Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.
Related Product Information for GCP-2 (CXCL6) active protein
GCP-2 is a connective tissue derived CXC chemokine that can signal through the CXCR1 and CXCR2 receptors. GCP-2 selectively attracts neutrophils and has also been shown to exert anti-angiogenic activity. Human GCP-2 is cross-react on murine cells. Recombinant human GCP-2 is a 7.9 kDa protein containing 72 amino acid residues.
Product Categories/Family for GCP-2 (CXCL6) active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
8.0 kDa
NCBI Official Full Name
Bibrotoxin
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 6
NCBI Official Symbol
CXCL6
NCBI Official Synonym Symbols
GCP2; CKA-3; GCP-2; SCYB6
NCBI Protein Information
C-X-C motif chemokine 6; chemokine alpha 3; small-inducible cytokine B6; granulocyte chemotactic protein 2; Small inducible cytokine subfamily B (Cys-X-Cys), member b; chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2); small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)
UniProt Protein Name
Bibrotoxin
UniProt Gene Name
BTX
UniProt Synonym Gene Names
BTX
UniProt Entry Name
SRTXB_ATRBI
Uniprot Description
Function: Vasoconstrictor activity. These toxins cause cardiac arrest probably as a result of coronary vasospasm. May act by displaying agonistic activities towards endothelin-1 and -2 receptors (EDNRA and EDNRB). Ref.1
Subcellular location: Secreted.
Tissue specificity: Expressed by the venom gland.
Sequence similarities: Belongs to the endothelin/sarafotoxin family.
Research Articles on GCP-2 (CXCL6)
Similar Products
Product Notes
The GCP-2 (CXCL6) btx (Catalog #AAA691780) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human GCP-2 (CXCL6) reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: VLTELRCTCL RVTLRVNPKT IGKLQVFPAG PQCSKVEVVA SLKNGK QVCL DPEAPFLKKV IQKILDSGNK KN. It is sometimes possible for the material contained within the vial of "GCP-2 (CXCL6), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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