FGF-7/KGF active protein
Human FGF-7/KGF
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. Studies of mouse and rat homologs of this gene implicated roles in morphogenesis of epithelium, reepithelialization of wounds, hair development and early lung organogenesis. [provided by RefSeq, Jul 2008]
Uniprot Description
Function: Plays an important role in the regulation of embryonic development, cell proliferation and cell differentiation. Required for normal branching morphogenesis. Growth factor active on keratinocytes. Possible major paracrine effector of normal epithelial cell proliferation. Ref.4 Ref.6
Subunit structure: Interacts with FGFBP1. Interacts with FGFR2. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by heparan sulfate glycosaminoglycans that function as coreceptors. Ref.4 Ref.5 Ref.6
Subcellular location: Secreted.
Tissue specificity: Epithelial cell.
Sequence similarities: Belongs to the heparin-binding growth factors family.
Research Articles on FGF-7/KGF
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Product Notes
The FGF-7/KGF fgf7 (Catalog #AAA691905) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human FGF-7/KGF reacts with Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: MCNDMTPEQM ATNVNCSSPE RHTRSYDYME GGDIRVRRLF CRTQWY LRID KRGKVKGTQE MKNNYNIMEI RTVAVGIVAI KGVESEFYLA M NKEGKLYAK KECNEDCNFK ELILENHYNT YASAKWTHNG GEMFVAL NQK GIPVRGKKTK KEQKTAHFLP MAIT. It is sometimes possible for the material contained within the vial of "FGF-7/KGF, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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