Testing Data
CXCL16 active protein
Human CXCL16
Gene Names
CXCL16; SRPSOX; CXCLG16; SR-PSOX
Reactivity
Species Reactivity: Human
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
CXCL16; Human CXCL16; Recombinant Human CXCL16; CXCL16 active protein
Host
E Coli
Reactivity
Species Reactivity: Human
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
NEGSVTGSC YCGKRISSD SPPSVQFMN RLRKHLRAY HRCLYYTRF QLLSWSVCG GNKDPWVQE LMSCLDLKE CGHAYSGIV AHQKHLLP
Biological Activity
Determined by it's ability to chemoattract activated lymphocytes using a concentration of 1.0-100.0 ng/ml.
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for CXCL16 active protein
CXCL16 is a member of the CXC chemokine family and signals through the CXCR6 receptor. CXCL16 may play a role in attracting lymphocyte subsets during inflammation and may facilitate certain immune responses. The chemokine domain of CXCL16 contains six cysteine residues including the four highly conserved cysteine residues characteristic of CXC chemokines. The CXCL16 gene codes for a 273 amino acid polypeptide, which includes a 29 amino acid cytoplasmic domain and transmembrane sequence containing approximately 20 amino acids. The extracellular portion of CXCL16 contains a chemokines domain and an extended C-terminal "mucin-like stalk" sequence. The extracellular domain contains 89 amino acid residues (86 a.a. residues for the murine homolog). Recombinant human CXCL16 is a 10.1 kDa protein containing 89 amino acid residues.
Product Categories/Family for CXCL16 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
27,579 Da
NCBI Official Full Name
C-X-C motif chemokine 16
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 16
NCBI Official Symbol
CXCL16
NCBI Official Synonym Symbols
SRPSOX; CXCLG16; SR-PSOX
NCBI Protein Information
C-X-C motif chemokine 16; CXC chemokine ligand 16; small-inducible cytokine B16; transmembrane chemokine CXCL16; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
UniProt Protein Name
C-X-C motif chemokine 16
Protein Family
UniProt Gene Name
CXCL16
UniProt Synonym Gene Names
SCYB16; SRPSOX; SR-PSOX
UniProt Entry Name
CXL16_HUMAN
Uniprot Description
CXCL16: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 17p13
Cellular Component: extracellular space; membrane; integral to membrane; plasma membrane; extracellular region
Molecular Function: low-density lipoprotein receptor activity; chemokine activity; scavenger receptor activity
Biological Process: receptor-mediated endocytosis; response to cytokine stimulus; chemotaxis; positive regulation of cell growth; positive regulation of cell migration
Research Articles on CXCL16
Similar Products
Product Notes
The CXCL16 cxcl16 (Catalog #AAA696192) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Human CXCL16 reacts with Species Reactivity: Human and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: NEGSVTGSC YCGKRISSD SPPSVQFMN RLRKHLRAY HRCLYYTRF QLLSWSVCG GNKDPWVQE LMSCLDLKE CGHAYSGIV AHQKHLLP. It is sometimes possible for the material contained within the vial of "CXCL16, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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