mcp5 active protein
MCP5, Recombinant, Mouse (Macrophage/Monocyte Chemotactic Protein 5)
Gene Names
mcp5; mug21; num1
Purity
Highly PurifiedGreater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of (1EU/ug) of murine MCP-5.
Synonyms
MCP5; Recombinant; Mouse (Macrophage/Monocyte Chemotactic Protein 5); mcp5 active protein
Host
E Coli
Purity/Purification
Highly Purified
Greater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of (1EU/ug) of murine MCP-5.
Greater than 99% by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng perug of (1EU/ug) of murine MCP-5.
Form/Format
Lyophilized protein with no additives.
Biological Activity
The biological activity of murine MCP-5 was determined by a chemotaxis assay using human peripheral blood monocytes. Significant chemotaxis was achieved using a concentration of 50 ng/ml.
Reconstitution
The lyophilized murine MCP-5 is soluble in water and most aqueous buffers. The lyophilized protein can be reconstituted in water to a concentration of 1.0 mg/ml. This solution can be diluted into other buffered solutions or stored at -20 degree C for future use.
Preparation and Storage
-20 degree C
Stability: The lyophilized murine MCP-5, though stable at room temperature, is best stored desiccated below 0 degree C. Reconstituted murine MCP-5 should be stored in working aliquots at -20 degree C.
Stability: The lyophilized murine MCP-5, though stable at room temperature, is best stored desiccated below 0 degree C. Reconstituted murine MCP-5 should be stored in working aliquots at -20 degree C.
Related Product Information for mcp5 active protein
Murine macrophage/monocyte chemotactic protein-5 (MCP-5) is a member of the beta-chemokine family (C-C) of cytokines. This chemokine is strongly chemotactic for human monocytes and murine peritoneal macrophages, but is not active on mouse neutrophils and shows only a weak response on mouse eosinophils at high concentrations. Murine MCP-5 is a peptide of 9.2kD that consists of 82 amino acid residues.
Product Categories/Family for mcp5 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9.3kD
NCBI Official Full Name
Meiotic coiled-coil protein 5
NCBI Official Symbol
mcp5
NCBI Official Synonym Symbols
mug21; num1
NCBI Protein Information
cortical anchoring factor for dynein Mcp5/Num1
UniProt Protein Name
Meiotic coiled-coil protein 5
Protein Family
UniProt Gene Name
mcp5
UniProt Synonym Gene Names
mug21; num1
UniProt Entry Name
MCP5_SCHPO
Uniprot Description
Function: Involved in chromosome segregation. Facilitates nuclear oscillation during meiotic prophase I, the 'horsetail' phase, by acting as a dynein anchor. Essential for anchoring dhc1 to the cortex. Required for proper sliding of the microtubules along the cell cortex, which leads to the proper U-turn movement of the nucleus. Ref.1 Ref.3 Ref.4
Subcellular location: Cytoplasm › cell cortex. Note: Localizes to the cell cortex during the 'horsetail' phase of mitosis. Ref.1 Ref.4 Ref.5
Sequence similarities: Contains 1 PH domain.
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Product Notes
The mcp5 mcp5 (Catalog #AAA651031) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MCP5, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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