Macrophage, Monocyte Chemotactic Protein 3 Active Protein | Ccl7 active protein
Macrophage, Monocyte Chemotactic Protein 3, Recombinant, Mouse (MCP-3, MARC)
Gene Names
Ccl7; fic; marc; mcp3; MCP-3; Scya7
Purity
Highly Purified98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
Synonyms
Macrophage; Monocyte Chemotactic Protein 3; Recombinant; Mouse (MCP-3; MARC); Ccl7 active protein
Host
E Coli
Purity/Purification
Highly Purified
98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
Form/Format
Supplied as a lyophilized powder. No additives.
Sequence
The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Ala-Gly-Pro.
Biological Activity
Murine MCP-3 is fully biologically active when compared to standard. The specific activity as determined by the ability of Murine MCP-3 to chemoattract Balb/C mouse spleen MNCs at 10-100ng/ml.
Dimers and Aggregates
1% as determined by silver-stained SDS-PAGE gel analysis.
Endotoxin Level
0.1ng/ug (IEU/ug) of Murine Monocyte Chemotactic Protein-3.
Protein Content
Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280nm.
2. Analysis by RP-HPLC, using a calibrated solution of Murine MCP-3 as a Reference Standard.
1. UV spectroscopy at 280nm.
2. Analysis by RP-HPLC, using a calibrated solution of Murine MCP-3 as a Reference Standard.
Reconstitution
Reconstitute the lyophilized MCP-3 in sterile 18MO-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile dH2O and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Ccl7 active protein
Recombinant Murine MCP-3 is a non-glycosylated, Polypeptide chain containing 74 amino acids and having a molecular mass of 8510 Dalton.
Product Categories/Family for Ccl7 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
10,999 Da
NCBI Official Full Name
monocyte chemotactic protein-3
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 7
NCBI Official Symbol
Ccl7
NCBI Official Synonym Symbols
fic; marc; mcp3; MCP-3; Scya7
NCBI Protein Information
C-C motif chemokine 7; RANTES/sis homolog; intercrine/chemokine MARC; small inducible cytokine A7; small-inducible cytokine A7; monocyte chemotactic protein 3; monocyte chemoattractant protein 3
UniProt Protein Name
C-C motif chemokine 7
Protein Family
UniProt Gene Name
Ccl7
UniProt Synonym Gene Names
Fic; Mcp3; Scya7; MCP-3
UniProt Entry Name
CCL7_MOUSE
Uniprot Description
Function: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity
By similarity.
Subunit structure: Monomer
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the intercrine beta (chemokine CC) family.
Research Articles on Ccl7
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Product Notes
The Ccl7 ccl7 (Catalog #AAA650066) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: The sequence of the first five N-terminal amino acids was determined and was found to be Gln-Pro-Al a-Gly-Pro. It is sometimes possible for the material contained within the vial of "Macrophage, Monocyte Chemotactic Protein 3, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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