SDS-Page
(Recombinant Human LRPAP Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at approximately 40 kDa.)
LRPAP active protein
Recombinant Human LRPAP Protein
After reconstitution, the protein solution is stable at -20 degree C for 3 months, at 2-8 degree C for up to 1 week.
SDS-Page
(Recombinant Human LRPAP Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at approximately 40 kDa.)
SDS-Page
(Recombinant Human LRPAP Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at approximately 40 kDa.)
Background: This protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that interacts with the low density lipoprotein (LDL) receptor-related protein and facilitates its proper folding and localization by preventing the binding of ligands. Mutations in this gene have been identified in individuals with myopia 23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Uniprot Description
LRPAP1: Interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. In complex with the alpha-2-MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis. Belongs to the alpha-2-MRAP family.
Protein type: Receptor, misc.
Chromosomal Location of Human Ortholog: 4p16.3
Cellular Component: cell surface; endoplasmic reticulum; extracellular region; plasma membrane; integral to membrane; vesicle
Molecular Function: heparin binding; receptor antagonist activity; protein binding; low-density lipoprotein receptor binding; unfolded protein binding; asialoglycoprotein receptor activity
Biological Process: vesicle-mediated transport; receptor-mediated endocytosis; protein folding; negative regulation of protein binding
Disease: Myopia 23, Autosomal Recessive
Research Articles on LRPAP
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Product Notes
The LRPAP lrpap1 (Catalog #AAA9139661) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: YSREKNQPKP SPKRESGEEF RMEKLNQLWE KAQRLHLPPV RLAELHADLK IQERDELAWK KLKLDGLDED GEKEARLIRN LNVILAKYGL DGKKDARQVT SNSLSGTQED GLDDPRLEKL WHKAKTSGKF SGEELDKLWR EFLHHKEKVH EYNVLLETLS RTEEIHENVI SPSDLSDIKG SVLHSRHTEL KEKLRSINQG LDRLRRVSHQ GYSTEAEFEE PRVIDLWDLA QSANLTDKEL EAFREELKHF EAKIEKHNHY QKQLEIAHEK LRHAESVGDG ERVSRSREKH ALLEGRTKEL GYTVKKHLQD LSGRISRARH NEL. It is sometimes possible for the material contained within the vial of "LRPAP, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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