Interleukin 9 Human Active Protein | IL9 active protein
Interleukin 9, Recombinant Human (IL-9)
Gene Names
IL9; P40; HP40; IL-9
Purity
Highly Purified98% by SDS-PAGE and HPLC analyses
Synonyms
Interleukin 9 Human; Interleukin 9; Recombinant Human (IL-9); IL9 active protein
Host
E Coli
Purity/Purification
Highly Purified
98% by SDS-PAGE and HPLC analyses
98% by SDS-PAGE and HPLC analyses
Form/Format
Supplied as a lyophilized powder with no additives.
Sequence
MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI
Biological Activity
Human IL-9 is fully biologically active when compared to standards. The ED50 was determined by the dose-dependent proliferation of human MO7e cells was 0.2ng/ml corresponding to a specific activity of 5x10e6u/mg.
Endotoxin Level
0.1ng/ug (1EU/ug)
Reconstitution
Reconstituted with sterile ddH2O to a concentration of 0.1-1.0mg/ml. Do not vortex.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for IL9 active protein
IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.kD protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.
Product Categories/Family for IL9 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14.1kD
NCBI Official Full Name
interleukin-9
NCBI Official Synonym Full Names
interleukin 9
NCBI Official Symbol
IL9
NCBI Official Synonym Symbols
P40; HP40; IL-9
NCBI Protein Information
interleukin-9; cytokine P40; p40 cytokine; OTTHUMP00000159423; T-cell growth factor p40; p40 T-cell and mast cell growth factor; homolog of mouse T cell and mast cell growth factor 40
UniProt Protein Name
Interleukin-9
Protein Family
UniProt Gene Name
IL9
UniProt Entry Name
IL9_HUMAN
NCBI Description
The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness. [provided by RefSeq]
Uniprot Description
Function: Supports IL-2 independent and IL-4 independent growth of helper T-cells.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-7/IL-9 family.
Research Articles on IL9
1. analysis of IL-9 and IL-9 receptor gene polymorphisms and atopic dermatitis in a Korean population
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Product Notes
The IL9 il9 (Catalog #AAA650004) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI. It is sometimes possible for the material contained within the vial of "Interleukin 9 Human, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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