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Interleukin 22 Active Protein | IL22 active protein

Interleukin 22, Recombinant, Human (IL-22, CRF2-9, IL-TIF R1, IL-10 Related T Cell-derived Inducible Factor)

Gene Names
IL22; TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23
Purity
Highly Purified
98% (SDS PAGE and HPLC).
Synonyms
Interleukin 22; Recombinant; Human (IL-22; CRF2-9; IL-TIF R1; IL-10 Related T Cell-derived Inducible Factor); IL22 active protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Highly Purified
98% (SDS PAGE and HPLC).
Form/Format
Supplied as a lyophilized powder. Reconstitute in 100ul distilled water.
Application Notes
Suitable for use in Functional Assays.
Biological Activity
Determined by its ability to activate STAT following receptor ligand interaction.
Endotoxin Level
1EU/ug
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for IL22 active protein
Interleukin-22 (IL-22) is a regulatory cytokine and member of the IL-10 family, secreted by activated T cells, which signals through a class II cytokine receptor system consisting of IL-22R and IL-10R-beta/CRF2-4. IL-22 has been shown to act as an inhibitor of the production of IL-4 by Th2 cells, up-regulate the production of acute phase reactants in the pancreas and liver, and to be up-regulated in intestinal inflammation associated with Crohn's disease.
Product Categories/Family for IL22 active protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
33.6kD (146 amino acid homodimer)
NCBI Official Full Name
interleukin-22
NCBI Official Synonym Full Names
interleukin 22
NCBI Official Symbol
IL22
NCBI Official Synonym Symbols
TIFa; IL-21; IL-22; ILTIF; IL-TIF; IL-D110; zcyto18; MGC79382; MGC79384; TIFIL-23
NCBI Protein Information
interleukin-22; cytokine Zcyto18; OTTHUMP00000240117; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor
UniProt Protein Name
Interleukin 22
Protein Family
UniProt Gene Name
IL22
UniProt Entry Name
Q6NWP4_HUMAN

Uniprot Description

IL22: Cytokine that contributes to the inflammatory response in vivo. Belongs to the IL-10 family.

Protein type: Secreted; Secreted, signal peptide; Cytokine

Chromosomal Location of Human Ortholog: 12q15

Cellular Component: extracellular space; extracellular region

Molecular Function: cytokine activity; interleukin-22 receptor binding

Biological Process: cell-cell signaling; response to glucocorticoid stimulus; acute-phase response; inflammatory response

Research Articles on IL22

Similar Products

Product Notes

The IL22 il22 (Catalog #AAA650280) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. Suitable for use in Functional Assays. Researchers should empirically determine the suitability of the IL22 il22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin 22, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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