Interferon-inducible T Cell Alpha Chemoattractant, Murine Active Protein | Cxcl11 active protein
Interferon-inducible T Cell Alpha Chemoattractant, Murine (I-TAC)
Gene Names
Cxcl11; Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11; Scyb9b; betaR1
Purity
Molecular Biology Grade98% by SDS-PAGE and HPLC analysis.
Synonyms
Interferon-inducible T Cell Alpha Chemoattractant; Murine; Murine (I-TAC); Cxcl11 active protein
Host
E Coli
Purity/Purification
Molecular Biology Grade
98% by SDS-PAGE and HPLC analysis.
98% by SDS-PAGE and HPLC analysis.
Form/Format
Sterile filtered and lyophilized without additives.
Sequence
FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRKQNM
Biological Activity
Determined by its ability to chemoattract murine CXCR3 transfected HEK/293 cells using a concentration range of 10-100ng/ml.
Country of Origin
USA
Endotoxin Level
0.1ng/ug (1EU/ug)
Reconstitution
Lyophilized human I-TAC is soluble in water and most aqueous buffers and can be reconstituted in water to a concentration of 0.1-1.0mg/ml. This solution can be diluted into other buffered solutions or stored frozen for future use.
Preparation and Storage
-20 degree C
Stability: Lyophilized protein, though stable at room temperature, is best stored desiccated below 0 degree C. Reconstituted I-TAC should be stored in working aliquots at-20 degree C.
Stability: Lyophilized protein, though stable at room temperature, is best stored desiccated below 0 degree C. Reconstituted I-TAC should be stored in working aliquots at-20 degree C.
Related Product Information for Cxcl11 active protein
Murine Interferon-inducible T cell alpha chemoattractant (I-TAC) is a novel non-ELR CXC chemokine. Murine I-TAC is regulated by interferon and has potent chemoattractant activity for IL-2 activated T cells, but not for freshly isolated unstimulated T cells, neutrophils, or monocytes. Recombinant Murine I-TAC is a 9kD protein containing 79 amino acid residues.
Product Categories/Family for Cxcl11 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
9.0kD
NCBI Official Full Name
interferon-inducible T cell alpha chemoattractant proprotein
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 11
NCBI Official Symbol
Cxcl11
NCBI Official Synonym Symbols
Ip9; H174; Itac; b-R1; Cxc11; I-tac; Scyb11; Scyb9b; betaR1
NCBI Protein Information
C-X-C motif chemokine 11; small-inducible cytokine B11; interferon-inducible T-cell alpha chemoattractant; small inducible cytokine subfamily B (Cys-X-Cys), member 11
UniProt Protein Name
C-X-C motif chemokine 11
Protein Family
UniProt Gene Name
Cxcl11
UniProt Synonym Gene Names
Scyb11; I-TAC
UniProt Entry Name
CXL11_MOUSE
Uniprot Description
CXCL11: Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses. Belongs to the intercrine alpha (chemokine CxC) family.
Protein type: Motility/polarity/chemotaxis; Chemokine; Secreted, signal peptide; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: CXCR3 chemokine receptor binding; chemokine activity; cytokine activity
Biological Process: G-protein coupled receptor protein signaling pathway; immune response; positive regulation of leukocyte chemotaxis; response to lipopolysaccharide; inflammatory response; chemotaxis; regulation of cell proliferation
Research Articles on Cxcl11
Similar Products
Product Notes
The Cxcl11 cxcl11 (Catalog #AAA634865) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: FLMFKQGRCL CIGPGMKAVK MAEIEKASVI YPSNGCDKVE VIVTMKAHKR QRCLDPRSKQ ARLIMQAIEK KNFLRKQNM. It is sometimes possible for the material contained within the vial of "Interferon-inducible T Cell Alpha Chemoattractant, Murine, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
