GRO/KC, Rat Active Protein | Cxcl1 active protein
GRO/KC, Recombinant, Rat (Cxcl1, Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity, alpha), Cinc1, CINC-1, C-X-C Motif Chemokine 1, Cytokine-induced Neutrophil Chemoattractant 1, Gro1, Growth-regulated alpha Protein, Platelet-derived
Gene Names
Cxcl1; Gro1; CINC-1
Purity
Molecular Biology Grade98% by SDS-PAGE and HPLC
Synonyms
GRO/KC; Rat; Recombinant; Rat (Cxcl1; Chemokine (C-X-C Motif) Ligand 1 (Melanoma Growth Stimulating Activity; alpha); Cinc1; CINC-1; C-X-C Motif Chemokine 1; Cytokine-induced Neutrophil Chemoattractant 1; Gro1; Growth-regulated alpha Protein; Platelet-derived; Cxcl1 active protein
Host
E Coli
Purity/Purification
Molecular Biology Grade
98% by SDS-PAGE and HPLC
98% by SDS-PAGE and HPLC
Form/Format
Supplied as a lyophilized powder. No additives. Reconstitute in sterile dH2O to 0.1-1mg/ml. This solution can then be diluted into other aqueous buffers.
Biological Activity
Determined by ability to chemoattract total rat neutrophils at a concentration range of 10-100ng/ml.
Endotoxin Level
0.1ng/ug
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute by adding sterile water, aliquot and store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for Cxcl1 active protein
All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant rat GRO/KC is a 7.8kD protein consisting of 72 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.
Product Categories/Family for Cxcl1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
7.8kD
NCBI Official Full Name
growth-regulated alpha protein
NCBI Official Synonym Full Names
chemokine (C-X-C motif) ligand 1
NCBI Official Symbol
Cxcl1
NCBI Official Synonym Symbols
Gro1; CINC-1
NCBI Protein Information
growth-regulated alpha protein; C-X-C motif chemokine 1; cytokine-induced neutrophil chemoattractant 1; platelet-derived growth factor-inducible protein KC; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
UniProt Protein Name
Growth-regulated alpha protein
Protein Family
UniProt Gene Name
Cxcl1
UniProt Synonym Gene Names
Cinc1; Gro; Scyb1; CINC-1
UniProt Entry Name
GROA_RAT
NCBI Description
acts as a neutrophil chemoattractant; may play a role in acute phase inflammatory response [RGD, Feb 2006]
Uniprot Description
Function: Has chemotactic activity for neutrophils. Contributes to neutrophil activation during inflammation.
Subunit structure: Monomer and homodimer.
Subcellular location: Secreted.
Tissue specificity: At least expressed in the lung and trachea.
Induction: By lipopolysaccharides (LPS) and inflammation.
Sequence similarities: Belongs to the intercrine alpha (chemokine CxC) family.
Research Articles on Cxcl1
Similar Products
Product Notes
The Cxcl1 cxcl1 (Catalog #AAA651024) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "GRO/KC, Rat, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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