Epidermal Growth Factor (rHuEGF) Active Protein | EGFR active protein
Recombinant Human Epidermal Growth Factor
Purity
Greater than 98% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain.Purification: Chromatographic
Synonyms
Epidermal Growth Factor (rHuEGF); Recombinant Human Epidermal Growth Factor; Recombinant Human Epidermal Growth Factor (rHuEGF); EGFR active protein
Host
E Coli
Specificity
Recombinant Human Epidermal Growth Factor (rHuEGF)
Purity/Purification
Greater than 98% by RP-HPLC, anion-exchange chromatography; reducing and non-reducing SDS-PAGE, silver stain.
Purification: Chromatographic
Purification: Chromatographic
Form/Format
Sterile filtered, lyophilized.
Sequence Length
71
Dimers/Aggregates
<1% by SDSPAGE
Biological Activity
Fully biologically active compared to reference standards. Specific activity of 1 x 10^7 Units/mg.
Endotoxin Level
<0.1 ng/ug
Protein Content
Determined spectrophotometrically at 280nm (2.858 ext. coeff), and by RP-HPLC analysis against a calibrated standard.
Solubility
Reconstitute the lyophilized product in sterile water not less than 100 ug/ml.
Preparation and Storage
Lyophilized product is stable at room temperature for 3 weeks. Store lyophilized product desiccated at -20 degree C. Upon reconstitution, store at 4 degree C for 2-7 days or aliquot and store at -20 degree C. For long-term storage add either HSA or BSA to 0.1%. Avoid repeated freeze-thaw cycles.
Related Product Information for EGFR active protein
Recombinant Human EGF produced in E. coli is a single chain, nonglycosylated polypeptide chain containing 53 amino acids with a molecular mass of 6,222 daltons. This product has full biological activity.
Product Categories/Family for EGFR active protein
NCBI and Uniprot Product Information
NCBI GI #
UniProt Accession #
Molecular Weight
7,519 Da
NCBI Official Full Name
epidermal growth factor
UniProt Protein Name
Epidermal growth factor
Protein Family
UniProt Gene Name
EGFR
UniProt Entry Name
Q8NDU8_HUMAN
NCBI Description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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Product Notes
The Epidermal Growth Factor (rHuEGF) egfr (Catalog #AAA197006) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Epidermal Growth Factor (rHuEGF), Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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