C-X-C motif chemokine 10 protein (Cxcl10) Active Protein | Cxcl10 active protein

Recombinant Mouse C-X-C motif chemokine 10 protein (Cxcl10) (Active)

Cat. Num. AAA969232

• Gene Names: Cxcl10; C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: C-X-C motif chemokine 10 protein (Cxcl10); Recombinant Mouse C-X-C motif chemokine 10 protein (Cxcl10) (Active); 10 kDa interferon gamma-induced protein; IP-10; C7; Interferon-gamma induced protein CRG-2; Small-inducible cytokine B10; Cxcl10 active protein

• Host: E Coli
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized
• Sequence Positions: 22-98aa
• Sequence: IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP
• Sequence Length: 98

• Species: Mus musculus (Mouse)
• Biological Activity: Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human peripheral blood lymphocytes is in a concentration range of 0.1- 10.0 ng/ml in the presence of IL-2.
• Endotoxin: Less than 1.0 EU/ug as determined by LAL method.
• Protein Note: Protein will be provided with aseptic processing and endotoxin removal.
• Preparation and Storage: Generally, the shelf life of liquid form is 6 months at -20/-80 degree C. The shelf life of lyophilized form is 12 months at -20/-80 degree C.

SDS-PAGE

Related Product Information for Cxcl10 active protein

In addition to its role as a proinflammatory cytokine, may participate in T-cell effector function and perhaps T-cell development.

Product Categories/Family for Cxcl10 active protein

Biological Active Protein; Immunology; Chemokine

NCBI and Uniprot Product Information

• NCBI GI #: 10946576
• NCBI GeneID: 15945
• NCBI Accession #: NP_067249.1
• NCBI GenBank Nucleotide #: NM_021274.2
• UniProt Accession #: P17515
• Molecular Weight: 8.7 kDa
• NCBI Official Full Name: C-X-C motif chemokine 10
• NCBI Official Synonym Full Names: chemokine (C-X-C motif) ligand 10
• NCBI Official Symbol: Cxcl10
• NCBI Official Synonym Symbols: C7; IP10; CRG-2; INP10; IP-10; Ifi10; mob-1; Scyb10; gIP-10
• NCBI Protein Information: C-X-C motif chemokine 10
• UniProt Protein Name: C-X-C motif chemokine 10
• Protein Family: C-X-C motif chemokine
• UniProt Gene Name: Cxcl10
• UniProt Synonym Gene Names: Crg2; Ifi10; Inp10; Scyb10; Gamma-IP10; IP-10

Uniprot Description

CXCL10: Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3. Belongs to the intercrine alpha (chemokine CxC) family.

Protein type: Chemokine; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 5 E2|5 46.57 cM

Cellular Component: external side of plasma membrane; extracellular region; extracellular space

Molecular Function: chemokine activity; CXCR3 chemokine receptor binding; heparin binding

Biological Process: chemotaxis; defense response to virus; endothelial cell activation; G-protein coupled receptor protein signaling pathway; immune response; inflammatory response; negative regulation of angiogenesis; negative regulation of myoblast differentiation; positive regulation of cAMP metabolic process; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of leukocyte chemotaxis; positive regulation of release of sequestered calcium ion into cytosol; regulation of cell proliferation; response to lipopolysaccharide