Human dynein, light chain, roadblock-type 1 ELISA Kit | DYNLRB1 elisa kit
Human Dynein light chain roadblock-type 1, DYNLRB1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene is a member of the roadblock dynein light chain family. The encoded cytoplasmic protein is capable of binding intermediate chain proteins, interacts with transforming growth factor-beta, and has been implicated in the regulation of actin modulating proteins. Upregulation of this gene has been associated with hepatocellular carcinomas, suggesting that this gene may be involved in tumor progression. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 12 and 18. [provided by RefSeq, Aug 2013]
Uniprot Description
DYNLRB1: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Belongs to the GAMAD family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 20q11.21
Cellular Component: microtubule; centrosome; membrane; cytoplasmic dynein complex; cytoplasm
Molecular Function: microtubule motor activity
Biological Process: transport; metabolic process; organelle organization and biogenesis; microtubule-based movement; visual behavior
Research Articles on DYNLRB1
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Product Notes
The Human DYNLRB1 dynlrb1 (Catalog #AAA9343274) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9343274 ELISA Kit recognizes Human DYNLRB1. It is sometimes possible for the material contained within the vial of "dynein, light chain, roadblock-type 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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