Mouse dual specificity phosphatase 13 ELISA Kit | DUSP13 elisa kit

Mouse Dual specificity protein phosphatase 13, DUSP13 ELISA Kit

Cat. Num. AAA9342421

• Gene Names: Dusp13; MDSP; TMDP; Gm1203; DUSP13A; DUSP13B; TS-DSP6; LMW-DSP6
• Reactivity: Mouse
• Synonyms: dual specificity phosphatase 13; Mouse Dual specificity protein phosphatase 13; DUSP13 ELISA Kit; Mouse Dual specificity protein phosphatase 13 (DUSP13) ELISA kit; RP11-487I5.6; BEDP; DUSP13A; DUSP13B; FLJ32450; MDSP; SKRP4; TMDP; OTTHUMP00000019875; branching-enzyme interacting dual-specificity protein phosphatase; dual-specificity phosphatase SKRP4; muscle-rest; DUSP13 elisa kit

• Reactivity: Mouse

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 56118225
• NCBI GeneID: 27389
• NCBI Accession #: NP_038877.2
• NCBI GenBank Nucleotide #: NM_013849.3
• UniProt Accession #: Q9QYJ7; Q497R2; Q6B8I0
• Molecular Weight: 22,481 Da
• NCBI Official Full Name: dual specificity protein phosphatase 13 isoform 2
• NCBI Official Synonym Full Names: dual specificity phosphatase 13
• NCBI Official Symbol: Dusp13
• NCBI Official Synonym Symbols: MDSP; TMDP; Gm1203; DUSP13A; DUSP13B; TS-DSP6; LMW-DSP6
• NCBI Protein Information: dual specificity protein phosphatase 13; Dsp13-like protein; muscle-restricted DSP; testis- and skeletal muscle-specific DSP; dual specificity tyrosine phosphatase TS-DSP6; dual-specificity tyrosine phosphatase TS-DSP6; dual specificity protein phosphatase isoform MDSP; testis and skeletal muscle-specific dual specificity phosphatase
• UniProt Protein Name: Dual specificity protein phosphatase 13 isoform B
• Protein Family: Dual specificity protein phosphatase
• UniProt Gene Name: Dusp13
• UniProt Synonym Gene Names: Gm1203; Tmdp; DUSP13B
• UniProt Entry Name: DS13B_MOUSE

NCBI Description

Members of the protein-tyrosine phosphatase superfamily cooperate with protein kinases to regulate cell proliferation and differentiation. This superfamily is separated into two families based on the substrate that is dephosphorylated. One family, the dual specificity phosphatases (DSPs) acts on both phosphotyrosine and phosphoserine/threonine residues. This gene encodes different but related DSP proteins through the use of non-overlapping open reading frames, alternate splicing, and presumed different transcription promoters. Expression of the distinct proteins from this gene has been found to be tissue specific and the proteins may be involved in postnatal development of specific tissues. A protein encoded by the upstream ORF was found in skeletal muscle, whereas the encoded protein from the downstream ORF was found only in testis. In humans, a similar pattern of expression was found. Multiple alternatively spliced transcript variants were described, but the full-length sequence of only some were determined. [provided by RefSeq, Jul 2008]

Uniprot Description

DUSP13: May be involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. Exhibits intrinsic phosphatase activity towards both phospho- seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 5 isoforms of the human protein are produced by alternative promoter.

Protein type: Protein phosphatase, dual-specificity; EC 3.1.3.48; EC 3.1.3.16; Motility/polarity/chemotaxis; Cell cycle regulation

Cellular Component: cytoplasm

Molecular Function: hydrolase activity; phosphoric monoester hydrolase activity; protein tyrosine/serine/threonine phosphatase activity; protein tyrosine phosphatase activity; phosphoprotein phosphatase activity

Biological Process: dephosphorylation; protein amino acid dephosphorylation