DRG1 recombinant protein
DRG1, 1-367aa, Human, His tag, E Coli
Gene Names
DRG1; NEDD3
Applications
SDS-Page
Purity
> 85% by SDS-PAGE
Synonyms
DRG1; 1-367aa; Human; His tag; E Coli; Developmentally regulated GTP binding protein 1; ADP-ribosylation factor-like 11; DRG1 recombinant protein
Host
E Coli
Purity/Purification
> 85% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 1mM EDTA
Concentration
0.5 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MGSSHHHHHH SSGLVPRGSH MSSTLAKIAE IEAEMARTQK NKATAHHLGL LKARLAKLRR ELITPKGGGG GGPGEGFDVA KTGDARIGFV GFPSVGKSTL LSNLAGVYSE VAAYEFTTLT TVPGVIRYKG AKIQLLDLPG IIEGAKDGKG RGRQVIAVAR TCNLILIVLD VLKPLGHKKI IENELEGFGI RLNSKPPNIG FKKKDKGGIN LTATCPQSEL DAETVKSILA EYKIHNADVT LRSDATADDL IDVVEGNRVY IPCIYVLNKI DQISIEELDI IYKVPHCVPI SAHHRWNFDD LLEKIWDYLK LVRIYTKPKG QLPDYTSPVV LPYSRTTVED FCMKIHKNLI KEFKYALVWG LSVKHNPQKV GKDHTLEDED VIQIVKK
Sequence Length
367
Applicable Applications for DRG1 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
Related Product Information for DRG1 recombinant protein
Developmentally-regulated GTP-binding protein 1 (DRG1) belong to the GTP1/OBG family. It plays a role in cell proliferation and differentiation, as well as in apoptosis, suggesting a role in tumor formation and metastasis. Expression of the DRG1 was significantly reduced in breast tumor cells, particularly in patients with lymph node or bone metastasis as compared to those with localized breast cancer. This protein expressed at high levels in heart, kidney and skeletal muscle and at lower levels in brain, liver, placenta, lung, colon and spleen. Recombinant human DRG1 protein, fused to His-tag at N-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for DRG1 recombinant protein
References
Sazuka, T., et al. (1992) Res. Commun. 189: 363-370.; Bandyopadhyay S., et al. (2004). Oncogene 23 (33): 5675-81.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
42.7kDa (387aa), confirmed by MALDI-TOF
NCBI Official Full Name
developmentally-regulated GTP-binding protein 1
NCBI Official Synonym Full Names
developmentally regulated GTP binding protein 1
NCBI Official Symbol
DRG1
NCBI Official Synonym Symbols
NEDD3
NCBI Protein Information
developmentally-regulated GTP-binding protein 1
UniProt Protein Name
Developmentally-regulated GTP-binding protein 1
Protein Family
UniProt Gene Name
DRG1
UniProt Synonym Gene Names
NEDD3; DRG-1; NEDD-3
Uniprot Description
Critical regulator of cell growth under specific conditions. Implicated in differentiation and cell cycle arrest.
