Rat down-regulator of transcription 1, TBP-binding (negative cofactor 2) ELISA Kit | DR1 elisa kit
Rat Protein Dr1, DR1 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DR1: The association of the DR1/DRAP1 heterodimer with TBP results in a functional repression of both activated and basal transcription of class II genes. This interaction precludes the formation of a transcription-competent complex by inhibiting the association of TFIIA and/or TFIIB with TBP. Can bind to DNA on its own. Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Heterodimer with DRAP1. DR1 exists in solution as a homotetramer that dissociates during interaction with TBP and then, after complexing with TBP, reassociates at a slow rate, to reconstitute the tetramer. Interacts with NFIL3. Component of the ADA2A-containing complex (ATAC), composed of CSRP2BP, KAT2A, TADA2L, TADA3L, ZZ3, MBIP, WDR5, YEATS2, CCDC101 and DR1. Belongs to the NC2 beta/DR1 family.
Protein type: Transcription, coactivator/corepressor
Cellular Component: nucleus
Molecular Function: protein heterodimerization activity; sequence-specific DNA binding
Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent
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Product Notes
The Rat DR1 dr1 (Catalog #AAA9331676) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9331676 ELISA Kit recognizes Rat DR1. It is sometimes possible for the material contained within the vial of "down-regulator of transcription 1, TBP-binding (negative cofactor 2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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