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DPY30 recombinant protein

Recombinant Human DPY30

Gene Names
DPY30; Cps25; Saf19; HDPY-30
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
DPY30; Recombinant Human DPY30; DPY30 Human; DPY30 Human Recombinant; Dpy-30 Homolog (C. Elegans); Dpy-30-Like Protein; Dpy-30L; Protein Dpy-30 Homolog; HDPY-30; Cps25; Saf19; Protein dpy-30 homolog; DPY30 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
DPY30 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 30% glycerol and 2mM DTT.
Sterile Filtered clear solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMEPEQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVDLQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN
Sequence Length
99
Related Product Information for DPY30 recombinant protein
DPY30 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 122 amino acids (1-99 a.a) and having a molecular mass of 13.6 kDa. DPY30 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for DPY30 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
11,250 Da
NCBI Official Full Name
protein dpy-30 homolog isoform 1
NCBI Official Synonym Full Names
dpy-30, histone methyltransferase complex regulatory subunit
NCBI Official Symbol
DPY30
NCBI Official Synonym Symbols
Cps25; Saf19; HDPY-30
NCBI Protein Information
protein dpy-30 homolog
UniProt Protein Name
Protein dpy-30 homolog
UniProt Gene Name
DPY30
UniProt Synonym Gene Names
Dpy-30L
UniProt Entry Name
DPY30_HUMAN

Uniprot Description

DPY30: As part of the MLL1/MLL complex, involved in the methylation of histone H3 at 'Lys-4', particularly trimethylation. Histone H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. May play some role in histone H3 acetylation. In a teratocarcinoma cell, plays a crucial role in retinoic acid-induced differentiation along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci. May also play an indirect or direct role in endosomal transport. Belongs to the dpy-30 family.

Chromosomal Location of Human Ortholog: 2p22.3

Cellular Component: Golgi apparatus; histone methyltransferase complex; nucleoplasm; nucleus; trans-Golgi network

Molecular Function: histone lysine N-methyltransferase activity (H3-K4 specific); histone-lysine N-methyltransferase activity; identical protein binding; protein binding; protein homodimerization activity

Biological Process: chromatin silencing at telomere; endosome transport; histone H3-K4 methylation

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Product Notes

The DPY30 dpy30 (Catalog #AAA140900) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMEP EQML EGQTQVAENP HSEYGLTDNV ERIVENEKIN AEKSSKQKVD LQSLPTRAYL DQTVVPILLQ GLAVLAKERP PNPIEFLASY LLKNKAQFED RN. It is sometimes possible for the material contained within the vial of "DPY30, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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