Hamster Dolichyl Phosphate-N-Acetylglucosaminephosphotransferase 1 ELISA Kit | DPAGT1 elisa kit
Hamster Dolichyl Phosphate-N-Acetylglucosaminephosphotransferase 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
A similar gene has been characterized in mice and encodes dolichyl pyrophosphate (Dol-P-P) phosphatase. This protein dephosphorylates dolichyl pyrophosphate so that it may be re-utilized as a glycosyl carrier lipid by the oligosaccharyltransferase multisubunit complex in the ER. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jun 2012]
Uniprot Description
DOLPP1: Required for efficient N-glycosylation. Necessary for maintaining optimal levels of dolichol-linked oligosaccharides. Hydrolyzes dolichyl pyrophosphate at a very high rate and dolichyl monophosphate at a much lower rate. Does not act on phosphatidate. Belongs to the dolichyldiphosphatase family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Endoplasmic reticulum; Glycan Metabolism - N-glycan biosynthesis; Membrane protein, multi-pass; EC 3.6.1.43; Membrane protein, integral; Hydrolase
Chromosomal Location of Human Ortholog: 9q34.1
Cellular Component: endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane
Molecular Function: dolichyldiphosphatase activity
Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; dolichyl diphosphate biosynthetic process; lipid biosynthetic process; protein amino acid N-linked glycosylation; protein amino acid N-linked glycosylation via asparagine; post-translational protein modification
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Product Notes
The Hamster DPAGT1 dolpp1 (Catalog #AAA070732) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA070732 ELISA Kit recognizes Hamster DPAGT1. It is sometimes possible for the material contained within the vial of "Dolichyl Phosphate-N-Acetylglucosaminephosphotransferase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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