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SLC24A5 blocking peptide

SLC24A5 Immunizing Peptide

Gene Names
SLC24A5; JSX; OCA6; NCKX5; SHEP4
Reactivity
Human, Mouse, Rat, Dog
Synonyms
SLC24A5; SLC24A5 Immunizing Peptide; solute carrier family 24; member 5; JSX; NCKX5; ion transporter JSX; solute carrier family 24 (sodium/potassium/calcium exchanger); SLC24A5 blocking peptide
Ordering
For Research Use Only!
Reactivity
Human, Mouse, Rat, Dog
Form/Format
100ug of dried peptide
Sequence
TTPDCRKKFWKN
Sequence Length
500
Preparation and Storage
Shipped at ambient temperature, store at -20 degree C

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
48,016 Da
NCBI Official Full Name
sodium/potassium/calcium exchanger 5
NCBI Official Synonym Full Names
solute carrier family 24 member 5
NCBI Official Symbol
SLC24A5
NCBI Official Synonym Symbols
JSX; OCA6; NCKX5; SHEP4
NCBI Protein Information
sodium/potassium/calcium exchanger 5
UniProt Protein Name
Sodium/potassium/calcium exchanger 5
UniProt Gene Name
SLC24A5
UniProt Synonym Gene Names
JSX; NCKX5
UniProt Entry Name
NCKX5_HUMAN

NCBI Description

This gene is a member of the potassium-dependent sodium/calcium exchanger family and encodes an intracellular membrane protein with 2 large hydrophilic loops and 2 sets of multiple transmembrane-spanning segments. Sequence variation in this gene has been associated with differences in skin pigmentation. [provided by RefSeq, Jul 2008]

Uniprot Description

SLC24A5: Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca(2+) and 1 K(+) in exchange for 4 Na(+). Belongs to the sodium/potassium/calcium exchanger family. SLC24A subfamily.

Protein type: Membrane protein, multi-pass; Transporter; Membrane protein, integral; Transporter, SLC family

Chromosomal Location of Human Ortholog: 15q21.1

Cellular Component: integral to plasma membrane; melanosome; trans-Golgi network; trans-Golgi network membrane

Molecular Function: calcium channel activity; calcium ion binding; calcium, potassium:sodium antiporter activity; potassium ion binding; sodium ion binding; symporter activity

Biological Process: cellular calcium ion homeostasis; ion transport; negative regulation of melanin biosynthetic process; potassium ion transport; response to stimulus

Disease: Skin/hair/eye Pigmentation, Variation In, 4

Research Articles on SLC24A5

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Product Notes

The SLC24A5 slc24a5 (Catalog #AAA426349) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The SLC24A5 Immunizing Peptide reacts with Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: TTPDCRKKFW KN. It is sometimes possible for the material contained within the vial of "SLC24A5, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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