RAD9A blocking peptide
RAD9A Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
Uniprot Description
RAD9A: a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair in response to DNA damage. Possesses a 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. Forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Use of alternative polyA sites has been noted for Rad9.
Protein type: Apoptosis; DNA replication; Deoxyribonuclease; Cell cycle regulation; EC 3.1.11.2
Chromosomal Location of Human Ortholog: 11q13.1-q13.2
Cellular Component: cytoplasm; nucleoplasm; nucleus
Molecular Function: 3'-5' exonuclease activity; enzyme binding; exodeoxyribonuclease III activity; histone deacetylase binding; protein binding; protein kinase binding; SH3 domain binding
Biological Process: DNA damage checkpoint; DNA repair; DNA replication; DNA replication checkpoint; intra-S DNA damage checkpoint; response to DNA damage stimulus
Research Articles on RAD9A
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Product Notes
The RAD9A rad9a (Catalog #AAA425149) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The RAD9A Immunizing Peptide reacts with Human, Mouse, Dog and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: C-QGPSPVLA EDSEGE. It is sometimes possible for the material contained within the vial of "RAD9A, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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