DnaJ Recombinant Protein | DNAJC24 recombinant protein
Recombinant Human DnaJ (Hsp40) Homolog, Subfamily C, Member 24
Gene Names
DNAJC24; DPH4; JJJ3; ZCSL3
Purity
Greater than 90% as determined by SDS-PAGE.
Synonyms
DnaJ; Recombinant Human DnaJ (Hsp40) Homolog; Subfamily C; Member 24; DNAJC24 Human; DnaJ (Hsp40) Homolog; Member 24 Human Recombinant; DnaJ homolog subfamily C member 24; DNAJC24; DPH4; JJJ3; ZCSL3; CSL-type zinc finger-containing protein 3; Diphthamide biosynthesis protein 4; DNAJC24 recombinant protein
Host
E Coli
Purity/Purification
Greater than 90% as determined by SDS-PAGE.
Form/Format
The DNAJC24 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGSMMAVEQM PKKDWYSILG ADPSANISDL KQKYQKLILM YHPDKQSTDV PAGTVEECVQ KFIEIDQAWK ILGNEETKRE YDLQRCEDDL RNVGPVDAQV YLEEMSWNEG DHSFYLSCRC GGKYSVSKDE AEEVSLISCD TCSLIIELLH YN.
Sequence Length
149
Related Product Information for DNAJC24 recombinant protein
Description: DNAJC24 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 172 amino acids (1-149 a.a.) and having a molecular mass of 19.5kDa. DNAJC24 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: DnaJ homolog subfamily C member 24 (DNAJC24) belongs to the ZCSL family of proteins and each contain one DPH-type zinc finger. DNAJC24 is involved in the synthesis of diphthamide, a protein found on translation elongation factor EF-2 which is the target of bacterial ADP-ribosylating toxins. DNAJC24 stimulates the ATPase activity of few Hsp70-type chaperones. DNAJC24 detected in heart, brain, spleen, lung, liver, kidney and testis.
Introduction: DnaJ homolog subfamily C member 24 (DNAJC24) belongs to the ZCSL family of proteins and each contain one DPH-type zinc finger. DNAJC24 is involved in the synthesis of diphthamide, a protein found on translation elongation factor EF-2 which is the target of bacterial ADP-ribosylating toxins. DNAJC24 stimulates the ATPase activity of few Hsp70-type chaperones. DNAJC24 detected in heart, brain, spleen, lung, liver, kidney and testis.
Product Categories/Family for DNAJC24 recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
9,693 Da
NCBI Official Full Name
dnaJ homolog subfamily C member 24
NCBI Official Synonym Full Names
DnaJ (Hsp40) homolog, subfamily C, member 24
NCBI Official Symbol
DNAJC24
NCBI Official Synonym Symbols
DPH4; JJJ3; ZCSL3
NCBI Protein Information
dnaJ homolog subfamily C member 24; 1700030A21Rik; CSL-type zinc finger-containing protein 3; DPH4 homolog (JJJ3, S. cerevisiae); DPH4, JJJ3 homolog; diphthamide biosynthesis protein 4; zinc finger, CSL domain containing 3; zinc finger, CSL-type containing 3
UniProt Protein Name
DnaJ homolog subfamily C member 24
Protein Family
UniProt Gene Name
DNAJC24
UniProt Synonym Gene Names
DPH4; ZCSL3
UniProt Entry Name
DJC24_HUMAN
NCBI Description
Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]
Uniprot Description
DNAJC24: Stimulates the ATPase activity of several Hsp70-type chaperones. Belongs to the DPH4 family.
Protein type: Enzyme, misc.; Chaperone
Chromosomal Location of Human Ortholog: 11p13
Cellular Component: cytoskeleton; cytoplasm
Molecular Function: ATPase activator activity; zinc ion binding; ferrous iron binding
Biological Process: positive regulation of ATPase activity; peptidyl-diphthamide biosynthetic process from peptidyl-histidine
Research Articles on DNAJC24
Similar Products
Product Notes
The DNAJC24 dnajc24 (Catalog #AAA146606) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGSMMA VEQM PKKDWYSILG ADPSANISDL KQKYQKLILM YHPDKQSTDV PAGTVEECVQ KFIEIDQAWK ILGNEETKRE YDLQRCEDDL RNVGPVDAQV YLEEMSWNEG DHSFYLSCRC GGKYSVSKDE AEEVSLISCD TCSLIIELLH YN.. It is sometimes possible for the material contained within the vial of "DnaJ, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
