DnaJ homolog subfamily B member 6 (Dnajb6) Recombinant Protein | Dnajb6 recombinant protein
Recombinant Rat DnaJ homolog subfamily B member 6 (Dnajb6)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
DnaJ homolog subfamily B member 6 (Dnajb6); Recombinant Rat DnaJ homolog subfamily B member 6 (Dnajb6); Dnajb6 recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-357, full length protein
Sequence
VDYYEVLGVQRHASPEDIKKAYRKQALKWHPDKNPENKEEAERKFKQVAEAYEVLSDAKKRDIYDKYGKEGLNGGGGGGGSHFDSPFEFGFTFRNPDDVFREFFGGRDPFSFDFFEDPFDDFFGNRRGPRGSRSRGAGSFFSAFSGFPSFGSGFPAFDTGFTPFGSLGHGGLTSFSSASFGGSGMGNFKSISTSTKIVNGKKITTKRIVENGQERVEVEEDGQLKSLTINGVADENALAEECRRRGQPTPALAPGPAPAPARVPSQARPPTPAPTPAPAQTPAPSVSTRPQKPPRPAPTAKLVSKSNWEDEEQDRQRVPGNCDAPMTSAGLKEGGKRKKQKQKEDSKKKKSTKGNH
Sequence Length
356
Species
Rat
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for Dnajb6 recombinant protein
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the J-domain and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants; however, not all variants have been fully described.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
38,922 Da
NCBI Official Full Name
dnaJ homolog subfamily B member 6
NCBI Official Synonym Full Names
DnaJ heat shock protein family (Hsp40) member B6
NCBI Official Symbol
Dnajb6
NCBI Protein Information
dnaJ homolog subfamily B member 6
UniProt Protein Name
DnaJ homolog subfamily B member 6
Protein Family
UniProt Gene Name
Dnajb6
UniProt Synonym Gene Names
HSJ-2
Uniprot Description
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (). Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70. Also reduces cellular toxicity and caspase-3 activity ().
Research Articles on Dnajb6
1. These results conclude that neurotoxicity resulting from elevated DNAJB6 is cell cycle dependent.
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Product Notes
The Dnajb6 dnajb6 (Catalog #AAA1346372) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-357, full length protein. The amino acid sequence is listed below: VDYYEVLGVQ RHASPEDIKK AYRKQALKWH PDKNPENKEE AERKFKQVAE AYEVLSDAKK RDIYDKYGKE GLNGGGGGGG SHFDSPFEFG FTFRNPDDVF REFFGGRDPF SFDFFEDPFD DFFGNRRGPR GSRSRGAGSF FSAFSGFPSF GSGFPAFDTG FTPFGSLGHG GLTSFSSASF GGSGMGNFKS ISTSTKIVNG KKITTKRIVE NGQERVEVEE DGQLKSLTIN GVADENALAE ECRRRGQPTP ALAPGPAPAP ARVPSQARPP TPAPTPAPAQ TPAPSVSTRP QKPPRPAPTA KLVSKSNWED EEQDRQRVPG NCDAPMTSAG LKEGGKRKKQ KQKEDSKKKK STKGNH. It is sometimes possible for the material contained within the vial of "DnaJ homolog subfamily B member 6 (Dnajb6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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