Human delta-like 4 (Drosophila) ELISA Kit | DLL4 elisa kit

Human Delta-like protein 4, DLL4 ELISA Kit

Cat. Num. AAA942396

• Gene Names: DLL4; hdelta2
• Reactivity: Human
• Synonyms: delta-like 4 (Drosophila); Human Delta-like protein 4; DLL4 ELISA Kit; Human Delta-like protein 4 (DLL4) ELISA kit; MGC126344; hdelta2; delta 4; delta ligand 4; delta-like 4 homolog; delta-like 4 protein; notch ligand DLL4; notch ligand delta-2; DLL4 elisa kit

• Reactivity: Human
• Specificity: This assay has high sensitivity and excellent specificity for detection of Human DLL4. No significant cross-reactivity or interference between Human DLL4 and analogues was observed.
• Sequence Length: 685

• Samples: Serum, plasma, tissue homogenates
• Detection Range: 23.5 pg/ml-1500 pg/ml
• Sensitivity: 5.8 pg/ml
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV% is less than 8%; Three samples of known concentration were tested twenty times on one plate to assess.; Inter-assay Precision (Precision between assays): CV% is less than 10%; Three samples of known concentration were tested in twenty assays to assess.
• Detection Wavelength: 450 nm
• Sample Volume: 50-100ul
• Protein Biological Process 1: Developmental Protein
• Protein Biological Process 3: Differentiation
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Typical Testing Data/Standard Curve (for reference only)

NCBI and Uniprot Product Information

• NCBI GI #: 9506545
• NCBI GeneID: 54567
• NCBI Accession #: NP_061947.1
• NCBI GenBank Nucleotide #: NM_019074.3
• UniProt Accession #: Q9NR61; Q3KP23; Q9NQT9
• Molecular Weight: 74,605 Da
• NCBI Official Full Name: delta-like protein 4
• NCBI Official Synonym Full Names: delta-like 4 (Drosophila)
• NCBI Official Symbol: DLL4
• NCBI Official Synonym Symbols: hdelta2
• NCBI Protein Information: delta-like protein 4; delta4; delta 4; delta ligand 4; notch ligand DLL4; delta-like 4 homolog; delta-like 4 protein; notch ligand delta-2; drosophila Delta homolog 4
• UniProt Protein Name: Delta-like protein 4
• Protein Family: Delta-like protein
• UniProt Gene Name: DLL4
• UniProt Synonym Gene Names: UNQ1895/PRO4341; Delta4
• UniProt Entry Name: DLL4_HUMAN

NCBI Description

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]

Uniprot Description

DLL4: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. Binds to Notch-1 and Notch-4. Expressed in vascular endothelium.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q14

Cellular Component: integral to membrane; plasma membrane

Molecular Function: calcium ion binding; Notch binding

Biological Process: patterning of blood vessels; negative regulation of cell proliferation; Notch signaling pathway; regulation of neurogenesis; visual perception; blood circulation; Notch receptor processing; blood vessel remodeling; angiogenesis; negative regulation of transcription from RNA polymerase II promoter; signal transduction