Delta-like protein 1 (Dll1) Recombinant Protein | Dll1 recombinant protein

Recombinant Rat Delta-like protein 1 (Dll1)

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Delta-like protein 1 (Dll1); Recombinant Rat Delta-like protein 1 (Dll1); Delta-like protein 1; Drosophila Delta homolog 1; Delta1; Dll1 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 18-537
• Sequence: QVW SSGVFELKLQ EFVNKKGLLG NRNCCRGGSG PPCACRTFFR VCLKHYQASV SPEPPCTYGS AVTAVLGVDS FSLPDGAGID PAFSNPIRFP FGFTWPGTFS LIIEALHTDS PDDLATENPE RLISRLTTQR HLTVGEEWSQ DLHSSGRTDL RYSYRFVCDE HYYGEGCSVF CRPRDDAFGH FTCGERGEKM CDPGWKGQYC TDPICLPGCD DQHGYCDKPG ECKCRVGWQG RYCDECIRYP GCLHGTCQQP WQCNCQEGWG GLFCNQDLNY CTHHKPCRNG ATCTNTGQGS YTCSCRPGYT GANCELEVDE CAPSPCRNGG SCTDLEDSYS CTCPPGFYGK VCELSAMTCA DGPCFNGGRC SDNPDGGYTC HCPAGFSGFN CEKKIDLCSS SPCSNGAKCV DLGNSYLCRC QTGFSGRYCE DNVDDCASSP CANGGTCRDS VNDFSCTCPP GYTGRNCSAP VSRCEHAPCH NGATCHQRGQ RYMCECAQGY GGANCQFLLP EPPPDLIVAA QGGSFPW
• Sequence Length: 520

• Species: Rattus norvegicus (Rat)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Dll1 recombinant protein

Dll1

NCBI and Uniprot Product Information

• NCBI GI #: 14091746
• NCBI GeneID: 84010
• NCBI Accession #: NP_114452.1
• NCBI GenBank Nucleotide #: NM_032063.2
• UniProt Accession #: P97677
• Molecular Weight: 77,379 Da
• NCBI Official Full Name: delta-like protein 1
• NCBI Official Synonym Full Names: delta-like 1 (Drosophila)
• NCBI Official Symbol: Dll1
• NCBI Protein Information: delta-like protein 1; delta1; drosophila Delta homolog 1
• UniProt Protein Name: Delta-like protein 1
• Protein Family: Delta-like protein
• UniProt Gene Name: Dll1
• UniProt Synonym Gene Names: Delta1
• UniProt Entry Name: DLL1_RAT

NCBI Description

homolog of the Notch Delta ligand; member of the delta/serrate/jagged family; may play a role in cell fate decisions during hematopoiesis [RGD, Feb 2006]

Uniprot Description

DLL1: Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Interacts with Notch receptors. Expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney.

Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Cell development/differentiation

Cellular Component: integral to membrane; plasma membrane; cytoplasmic vesicle

Molecular Function: calcium ion binding; Notch binding

Biological Process: nervous system development; somitogenesis; Notch signaling pathway; negative regulation of myeloid cell differentiation; negative regulation of interleukin-10 production; cell fate determination; compartment specification; negative regulation of neuron differentiation; negative regulation of cell differentiation; somite specification; regulation of neurogenesis; cell-cell signaling; negative regulation of auditory receptor cell differentiation; positive regulation of transcription from RNA polymerase II promoter; heart looping; determination of left/right symmetry; auditory receptor cell fate commitment; inner ear development; positive regulation of Notch signaling pathway