Mouse 24-dehydrocholesterol reductase ELISA Kit | DHCR24 elisa kit
Mouse Delta (24) -sterol reductase, DHCR24 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
Diminuto: the enzyme 3-beta-hydroxysterol delta-24-reductase (DHCR24), a member of the flavin adenine dinucleotide (FAD)-dependent oxidoreductases, catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. Highly expressed in brain and adrenal gland with moderate expression in liver, lung, spleen, prostate and spinal cord. Low expression in heart, uterus and prostate. Undetectable in blood cells. Overexpressed in the adenoma tissue of patients with Cushing's syndrome. May be involved in the molecular events of adrenocortical tumorigenesis by facilitating steroid synthesis and cell growth.
Protein type: Membrane protein, integral; Oxidoreductase; EC 1.3.1.72; Lipid Metabolism - steroid biosynthesis
Cellular Component: Golgi apparatus; cytoskeleton; membrane; endoplasmic reticulum; cytoplasm; integral to membrane; cytosol; nucleus
Molecular Function: delta24(24-1) sterol reductase activity; UDP-N-acetylmuramate dehydrogenase activity; enzyme binding; peptide antigen binding; FAD binding; oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; delta24-sterol reductase activity; oxidoreductase activity; catalytic activity; oxidoreductase activity, acting on CH-OH group of donors
Biological Process: skin development; steroid metabolic process; tissue development; cholesterol metabolic process; negative regulation of caspase activity; cholesterol biosynthetic process; negative regulation of cell proliferation; protein localization; amyloid precursor protein catabolic process; sterol biosynthetic process; Ras protein signal transduction; male genitalia development; lipid metabolic process; sterol metabolic process; steroid biosynthetic process; plasminogen activation; negative regulation of apoptosis
Research Articles on DHCR24
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Product Notes
The Mouse DHCR24 dhcr24 (Catalog #AAA9337355) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9337355 ELISA Kit recognizes Mouse DHCR24. It is sometimes possible for the material contained within the vial of "24-dehydrocholesterol reductase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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