Mouse deoxyguanosine kinase ELISA Kit | DGUOK elisa kit
Mouse Deoxyguanosine kinase, mitochondrial, DGUOK ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
DGUOK: Required for the phosphorylation of several deoxyribonucleosides and certain nucleoside analogs widely employed as antiviral and chemotherapeutic agents. Defects in DGUOK are the cause of mitochondrial DNA depletion syndrome type 3 (MTDPS3). A disorder characterized by onset in infancy of progressive liver failure, hypoglycemia, increased lactate in body fluids, and neurologic abnormalities including hypotonia, encephalopathy, peripheral neuropathy. Affected tissues show both decreased activity of the mtDNA-encoded respiratory chain complexes and mtDNA depletion. Belongs to the DCK/DGK family. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Mitochondrial; Nucleotide Metabolism - purine; Kinase, other; EC 2.7.1.113
Cellular Component: mitochondrion; cytoplasm; cytosol; nucleus
Molecular Function: transferase activity; nucleoside kinase activity; deoxyguanosine kinase activity; nucleotide binding; kinase activity; ATP binding
Biological Process: purine deoxyribonucleoside metabolic process; nucleotide biosynthetic process; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; dGTP metabolic process; phosphorylation; protein amino acid phosphorylation; deoxyribonucleoside monophosphate biosynthetic process
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Product Notes
The Mouse DGUOK dguok (Catalog #AAA9319035) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9319035 ELISA Kit recognizes Mouse DGUOK. It is sometimes possible for the material contained within the vial of "deoxyguanosine kinase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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