Scavenger mRNA-decapping enzyme DcpS (DCPS) Recombinant Protein | DCPS recombinant protein
Recombinant Bovine Scavenger mRNA-decapping enzyme DcpS (DCPS)
NCBI and Uniprot Product Information
Uniprot Description
Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG) with up to 10 nucleotide substrates (small capped oligoribonucleotides) and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP). Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7)GpppG) with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG) and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP) to m7GMP. May also play a role in the 5'->3 mRNA decay pathway; m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP. Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death.
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Product Notes
The DCPS dcps (Catalog #AAA1471313) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-337, full length protein. The amino acid sequence is listed below: AELAHQQSKR KRELDAEEAE ASSTEGEEAG VGNGTSAPVR LPFSGFRVKK VLRESARDKI IFLHGKVNEA SGDGDGEDAV VILEKTPFQV DQVAQLLKGS PELQLQFSND VYSTYHLFPP RQLSDVKTTV VYPATEKHLQ KYLRQDLHLV RETGSDYRNV TLPHLESQSL SIQWVYNILD KKAEADRIVF ENPDPSDGFV LIPDLKWNQQ QLDDLYLIAI CHRRGIKSLR DLTAEHLPLL RNILREGQEA ILRRYQVAAD RLRVYLHYLP SYYHLHVHFT ALGFEAPGAG VERAHLLAEV IDNLEQDPEH YQRRTLTFAL RADDPLLALL QEAQRS. It is sometimes possible for the material contained within the vial of "Scavenger mRNA-decapping enzyme DcpS (DCPS), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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