Mouse decorin ELISA Kit | DCN elisa kit
Mouse Decorin, DCN ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Uniprot Description
DCN: May affect the rate of fibrils formation. Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD). Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. 5 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted; Extracellular matrix; Motility/polarity/chemotaxis
Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; extracellular region; collagen type VI
Molecular Function: collagen binding; glycosaminoglycan binding; extracellular matrix binding; protein N-terminus binding
Biological Process: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
Research Articles on DCN
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Product Notes
The Mouse DCN dcn (Catalog #AAA933682) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA933682 ELISA Kit recognizes Mouse DCN. It is sometimes possible for the material contained within the vial of "decorin, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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