Rat Dopamine beta-hydroxylase ELISA Kit | Dbh elisa kit
Rat Dopamine beta-hydroxylase ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
oxidoreductase that catalyzes the conversion of 3,4 dihydroxyphenethylamine, ascorbate, and O(2) to noradrenaline, dehydroascorbate, and H(2) in norephinephrine biosynthesis [RGD, Feb 2006]
Uniprot Description
DBH: Conversion of dopamine to noradrenaline. Homotetramer composed of two non-covalently bound disulfide-linked dimers. Activity is enhanced by nerve growth factor (in superior cervical ganglia and adrenal medulla). Trans-synaptic stimulation with reserpine, acetylcholine and glucocorticoids. Belongs to the copper type II ascorbate-dependent monooxygenase family.
Protein type: Oxidoreductase; EC 1.14.17.1; Cell cycle regulation; Membrane protein, integral; Motility/polarity/chemotaxis; Apoptosis; Amino Acid Metabolism - tyrosine
Cellular Component: apical part of cell; axon; cell soma; cytoplasm; cytoplasmic membrane-bound vesicle; dendrite; integral to membrane; synapse; terminal button
Molecular Function: copper ion binding; dopamine beta-monooxygenase activity; L-ascorbic acid binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
Biological Process: associative learning; behavioral response to ethanol; blood vessel remodeling; catecholamine metabolic process; cytokine production; dopamine catabolic process; fear response; glucose homeostasis; homoiothermy; leukocyte mediated immunity; leukocyte migration; locomotory behavior; maternal behavior; memory; multicellular organismal aging; norepinephrine biosynthetic process; octopamine metabolic process; positive regulation of vasoconstriction; regulation of cell proliferation; response to amphetamine; response to copper ion; response to drug; response to estradiol stimulus; response to ethanol; response to iron ion; response to organic cyclic substance; response to ozone; response to pain; response to peptide hormone stimulus; sensory perception of taste; social behavior; visual learning