Cell cycle protein kinase DBF2 (DBF2) Recombinant Protein | DBF2 recombinant protein

Recombinant Saccharomyces cerevisiae Cell cycle protein kinase DBF2 (DBF2) , partial

• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Cell cycle protein kinase DBF2 (DBF2); Recombinant Saccharomyces cerevisiae Cell cycle protein kinase DBF2 (DBF2); partial; DBF2 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 572

• Species: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 398365629
• NCBI GeneID: 852984
• NCBI Accession #: NP_011606.3
• NCBI GenBank Nucleotide #: NM_001181221.3
• UniProt Accession #: P22204; D6VUM4
• Molecular Weight: 66,148 Da
• NCBI Official Full Name: serine/threonine-protein kinase DBF2
• NCBI Official Symbol: DBF2
• NCBI Protein Information: serine/threonine-protein kinase DBF2
• UniProt Protein Name: Cell cycle protein kinase DBF2
• Protein Family: Cell cycle protein kinase
• UniProt Gene Name: DBF2

Uniprot Description

Ser/Thr-protein kinase involved in the mitotic exit network (MEN) and required after the metaphase to anaphase cell cycle transition. Phosphorylates CHS2 to regulate its dynamics and chitin synthesis at the division site during cytokinesis. Coordinates septin and actomyosin ring (AMR) functions during cytokinesis through the phosphorylation of HOF1. In complex with MOB1, phosphorylates CDC14 at sites adjacent to its nuclear localization sequence, thereby retaining CDC14 in the cytoplasm. Binds also to SWI5 and CLB2 mRNAs cotranscriptionally to regulate their decay. In the nucleus, the DBF2-MOB1 complex regulates passenger protein localization during anaphase. Mediates sorbic acid stress tolerance through promoting vacuolar H+-ATPase function, probably through phosphorylation of VMA1 and VMA2 subunits.