Cytokeratin 19, CK19 Recombinant Protein | CK19 recombinant protein
Cytokeratin 19, CK19 Protein (Active)
Applications
ELISA, SDS-Page
Purity
>95% by SDS-PAGE
Synonyms
Cytokeratin 19; CK19; CK19 Protein (Active); Keratin type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19; KRT19; CK19 recombinant protein
Host
E. Coli
Purity/Purification
>95% by SDS-PAGE
Form/Format
Liquid; Each vial contains Tris-HCl (pH7.4 ± 0.2) with 0.2% sodium azide.
Concentration
3 mg/ml (varies by lot)
Applicable Applications for CK19 recombinant protein
ELISA (EIA), SDS-PAGE
Application Notes
Other applications have not been tested.
The optimal dilutions should be determined by end user.
The optimal dilutions should be determined by end user.
Preparation and Storage
Upon receipt, aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze and thaw cycles.
Related Product Information for CK19 recombinant protein
Description:
Recombinant full length human Cytokeratin 19 protein with molecular weight 40 kDa.
Background:
Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have prognostic significance in some types of human malignancy. Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate identification of papillary carcinoma than the other combinations.
Recombinant full length human Cytokeratin 19 protein with molecular weight 40 kDa.
Background:
Cytokeratin 19 (CK19) belongs to a family of keratins, which are normally expressed in the lining of the gastroenteropancreatic and hepatobiliary tracts. It has been shown to be an independent prognostic factor for pancreatic neuroendocrine tumors, especially the insulin-negative tumors. CK19 positive tumors are associated with poor outcome irrespective of the established pathologic parameters such as size, mitoses, lymphovascular invasion, and necrosis. The low-molecular-weight cytokeratin (CK) protein CK19 has been shown to have prognostic significance in some types of human malignancy. Cytokeratin-19 alone and its combinations with other markers were more sensitive in accurate identification of papillary carcinoma than the other combinations.
References
1. Jain R, Fischer S, Serra S, Chetty R. The use of Cytokeratin 19 (CK19) immunohistochemistry in lesions of the pancreas, gastrointestinal tract, and liver. Appl Immunohistochem Mol Morphol. 2010; 18(1):9-15. 2. Stewart CJ, Crook ML, Lacey J, Louwen K. Cytokeratin 19 expression in normal endometrium and in low-grade endometrioid adenocarcinoma of the endometrium. Int J Gynecol Pathol. 2011; 30(5):484-91. 3. Barut F, Onak Kandemir N, Bektas S, Bahadir B, Keser S, Ozdamar SO. Universal markers of thyroid malignancies: galectin-3, HBME-1, and cytokeratin-19. Endocr Pathol. 2010; 21(2):80-9.
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Product Notes
The CK19 (Catalog #AAA355584) is a Recombinant Protein produced from E. Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cytokeratin 19, CK19 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), SDS-PAGE. Other applications have not been tested. The optimal dilutions should be determined by end user. Researchers should empirically determine the suitability of the CK19 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytokeratin 19, CK19, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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