Rat Cytochrome P450 3A2 ELISA Kit | Cyp3a2 elisa kit
Rat Cytochrome P450 3A2 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
catalyzes the conversion of testosterone to 6-beta-hydroxytestosterone [RGD, Feb 2006]
Uniprot Description
CYP3A4: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1'-hydroxylation and midazolam 4- hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2- exo-monooxygenase. The enzyme also hydroxylates etoposide. Belongs to the cytochrome P450 family.
Protein type: Cell surface; Demethylase; Oxidoreductase; Endoplasmic reticulum; Membrane protein, peripheral; Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - other enzymes; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - linoleic acid; Membrane protein, integral; EC 1.14.14.1; Xenobiotic Metabolism - metabolism by cytochrome P450
Cellular Component: cytoplasm; endoplasmic reticulum membrane
Molecular Function: demethylase activity; enzyme binding; heme binding; iron ion binding; monooxygenase activity; oxidoreductase activity; steroid binding; steroid hydroxylase activity; testosterone 6-beta-hydroxylase activity; vitamin D3 25-hydroxylase activity
Biological Process: alkaloid catabolic process; drug catabolic process; drug metabolic process; exogenous drug catabolic process; heterocycle metabolic process; monoterpenoid metabolic process; steroid catabolic process; steroid metabolic process
Research Articles on Cyp3a2
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Product Notes
The Rat Cyp3a2 cyp3a2 (Catalog #AAA2882873) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2882873 ELISA Kit recognizes Rat Cyp3a2. It is sometimes possible for the material contained within the vial of "Cytochrome P450 3A2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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