Coxsackievirus and adenovirus receptor homolog (Cxadr) Recombinant Protein | Cxadr recombinant protein

Recombinant Rat Coxsackievirus and adenovirus receptor homolog (Cxadr), partial

Cat. Num. AAA1416935

• Gene Names: Cxadr; Car1
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Coxsackievirus and adenovirus receptor homolog (Cxadr); Recombinant Rat Coxsackievirus and adenovirus receptor homolog (Cxadr); partial; Cxadr recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 20-238
• Sequence: L SITTPEQRIE KAKGETAYLP CKFTLEPEDQ GPLDIEWLIS PSDNQKVDQV IILYSGDKIY DNYYPDLKGR VHFTSNDVKS GDASINVTNL QLSDIGTYQC KVKKAPGVAN RKFLLTVLVK PSGTRCFVDG SGEIGNDFKL KCEPKEGSLP LQYEWQKLSD SQKMPTPWLA EMTSPVISVK NASSEYSGTY SCTVQNRVGS DQCMLRLDVV PPSNRAGT
• Sequence Length: 219

• Species: Rat
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Cxadr recombinant protein

This protein is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.

NCBI and Uniprot Product Information

• NCBI GI #: 56961616
• NCBI GeneID: 89843
• NCBI Accession #: NP_446022.1
• NCBI GenBank Nucleotide #: NM_053570.1
• UniProt Accession #: Q9R066; Q5M817; Q9R067
• Molecular Weight: 38,799 Da
• NCBI Official Full Name: coxsackievirus and adenovirus receptor homolog
• NCBI Official Synonym Full Names: CXADR, Ig-like cell adhesion molecule
• NCBI Official Symbol: Cxadr
• NCBI Official Synonym Symbols: Car1
• NCBI Protein Information: coxsackievirus and adenovirus receptor homolog
• UniProt Protein Name: Coxsackievirus and adenovirus receptor homolog
• Protein Family: Coxsackievirus and adenovirus receptor
• UniProt Gene Name: Cxadr
• UniProt Synonym Gene Names: Car; CAR; rCAR

NCBI Description

cell surface receptor for adenovirus and coxsackie virus; may be a barrier for macromolecule and ion movement across membranes in polarized epithelial cells [RGD, Feb 2006]

Uniprot Description

Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair ().