Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ZNF395 Polyclonal Antibody at dilution 1:40)
Rabbit ZNF395 Polyclonal Antibody | anti-ZNF395 antibody
ZNF395 Polyclonal Antibody
Gene Names
ZNF395; PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ZNF395; Polyclonal Antibody; ZNF395 Polyclonal Antibody; PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14; anti-ZNF395 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.5mg/mL (varies by lot)
Sequence Length
513
Applicable Applications for anti-ZNF395 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:200
Immunogen
Synthetic peptide of human ZNF395
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ZNF395 Polyclonal Antibody at dilution 1:40)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using ZNF395 Polyclonal Antibody at dilution 1:40)
Related Product Information for anti-ZNF395 antibody
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF395 (Zinc finger protein 395), also known as PBF (Papillomavirus-binding factor) and HDBP2 (Huntington disease gene regulatory region-binding protein 2), is a 513 amino acid protein that contains one C2H2-type zinc finger. ZNF395 binds to the 3'-CCGG-5' sequence within the papillomavirus promoter adjacent to a RUNX1-binding motif. It has also been established that ZNF395 binds to a seven base pair region within the Huntington's disease (HD) gene promoter, an essential element for HD gene expression. ZNF395 is widely expressed and probably shuttles between the nucleus and cytoplasm.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
54,939 Da
NCBI Official Full Name
zinc finger protein 395
NCBI Official Synonym Full Names
zinc finger protein 395
NCBI Official Symbol
ZNF395
NCBI Official Synonym Symbols
PBF; PRF1; HDBP2; PRF-1; HDBP-2; HDRF-2; Si-1-8-14
NCBI Protein Information
zinc finger protein 395; HD gene regulatory region-binding protein 2; HD-regulating factor 2; Huntington's disease gene regulatory region-binding protein 2; huntington disease gene regulatory region-binding protein 2; papillomavirus regulatory factor 1; papillomavirus regulatory factor PRF-1; papillomavirus-binding factor
UniProt Protein Name
Zinc finger protein 395
Protein Family
UniProt Gene Name
ZNF395
UniProt Synonym Gene Names
HDBP2; PBF; HDRF-2; HD gene regulatory region-binding protein 2; HDBP-2; PRF-1
UniProt Entry Name
ZN395_HUMAN
Uniprot Description
ZNF395: Plays a role in papillomavirus genes transcription.
Protein type: Transcription factor; C2H2-type zinc finger protein
Chromosomal Location of Human Ortholog: 8p21.1
Cellular Component: cytoplasm; nucleus
Molecular Function: DNA binding; metal ion binding
Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
Research Articles on ZNF395
Similar Products
Product Notes
The ZNF395 znf395 (Catalog #AAA2523392) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ZNF395 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ZNF395 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:200. Researchers should empirically determine the suitability of the ZNF395 znf395 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ZNF395, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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