Typical Testing Data/Standard Curve (for reference only)
Mouse CX3C chemokine receptor 1 ELISA Kit | Cx3cr1 elisa kit
Mouse CX3C chemokine receptor 1 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
Uniprot Description
CX3CR1: Receptor for the CX3C chemokine fractalkine and mediates both its adhesive and migratory functions. Acts as coreceptor with CD4 for HIV-1 virus envelope protein (in vitro). Isoform 2 and isoform 3 seem to be more potent HIV-1 coreceptors than isoform 1. Defects in CX3CR1 are a cause of susceptibility to age- related macular degeneration type 12 (ARMD12). ARMD12 is a form of age-related macular degeneration, a multifactorial eye disease and the most common cause of irreversible vision loss in the developed world. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid that lie beneath the retinal pigment epithelium and within an elastin-containing structure known as Bruch membrane. Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 1; Motility/polarity/chemotaxis; Receptor, cytokine; Receptor, GPCR; Cell adhesion
Cellular Component: integral to membrane; membrane; neuron projection; perinuclear region of cytoplasm; plasma membrane
Molecular Function: C-X3-C chemokine receptor activity; G-protein coupled receptor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; signal transducer activity
Biological Process: cell adhesion; cerebral cortex cell migration; chemotaxis; cytokine and chemokine mediated signaling pathway; G-protein coupled receptor protein signaling pathway; macrophage chemotaxis; memory; microglial cell activation; microglial cell activation during immune response; negative regulation of angiogenesis; negative regulation of cell migration; negative regulation of chronic inflammatory response to non-antigenic stimulus; positive regulation of angiogenesis; positive regulation of neuroblast proliferation; signal transduction
Research Articles on Cx3cr1
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Product Notes
The Mouse Cx3cr1 cx3cr1 (Catalog #AAA2881503) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2881503 ELISA Kit recognizes Mouse Cx3cr1. It is sometimes possible for the material contained within the vial of "CX3C chemokine receptor 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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