Human Cathepsin V ELISA Kit | CTSL2 elisa kit

Cathepsin V (Human) OmniKine ELISA Kit

Cat. Num. AAA9502027

• Gene Names: CTSV; CTSU; CATL2; CTSL2
• Reactivity: Human
• Synonyms: Cathepsin V; Cathepsin V (Human) OmniKine ELISA Kit; Cathepsin L2; Cathepsin U; CATL2; CTSU; CTSV; CTSL2 elisa kit

• Reactivity: Human
• Specificity: The OmniKine Human Cathepsin V ELISA is capable of recognizing both recombinant and naturally produced Human Cathepsin V proteins. The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross-reactivity or interference.; Human: Cathepsin A, Cathepsin B, Cathepsin C, Cathepsin D, Cathepsin E, Cathepsin F, Cathepsin L, Cathepsin O, Cathepsin S, Cathepsin X/Z/P, Cystatin E/M, Fetuin A, Kininogen, Kininostatin
• Form/Format: 12 x 8-Well Microstrips
• Sequence Length: 334

• Samples: Plasma, serum, lysate
• Assay Type: Sandwich ELISA
• Detection Range: 63-4000 pg/ml
• Sensitivity: 63-4000 pg/ml
• Detection Method: Colorimetric 450 nm
• Subtype: None
• Preparation and Storage: Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Human Cathepsin V ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Human Cathepsin V proteins within the range of 63-4000 pg/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 320118898
• NCBI GeneID: 1515
• NCBI Accession #: NP_001188504.1
• NCBI GenBank Nucleotide #: NM_001201575.1
• UniProt Accession #: O60911; O60233; Q2TB86; Q5T1U0
• Molecular Weight: 37,329 Da
• NCBI Official Full Name: cathepsin L2 preproprotein
• NCBI Official Synonym Full Names: cathepsin V
• NCBI Official Symbol: CTSV
• NCBI Official Synonym Symbols: CTSU; CATL2; CTSL2
• NCBI Protein Information: cathepsin L2
• UniProt Protein Name: Cathepsin L2
• UniProt Gene Name: CTSV
• UniProt Synonym Gene Names: CATL2; CTSL2; CTSU

NCBI Description

The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may play an important role in corneal physiology. This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2011]

Uniprot Description

CTSL2: Cysteine protease. May have an important role in corneal physiology. Belongs to the peptidase C1 family.

Protein type: EC 3.4.22.15; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 9q22.33

Cellular Component: apical part of cell; external side of plasma membrane; extracellular region; extracellular space; lysosomal lumen; lysosome; microvillus; neuron projection; perikaryon; secretory granule

Molecular Function: aminopeptidase activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; kininogen binding; peptide binding; protein binding; protein complex binding; serine-type endopeptidase activity

Biological Process: antigen processing and presentation of exogenous peptide antigen via MHC class II; autophagic cell death; cellular response to starvation; decidualization; extracellular matrix disassembly; multicellular organismal aging; nerve development; proteolysis involved in cellular protein catabolic process; regulation of keratinocyte differentiation; response to glucocorticoid stimulus; response to glucose stimulus; Sertoli cell differentiation; spermatogenesis