CTD small phosphatase-like protein (Ctdspl) Recombinant Protein | Ctdspl recombinant protein

Recombinant Mouse CTD small phosphatase-like protein (Ctdspl)

Cat. Num. AAA967036

• Gene Names: Ctdspl; SCP3; HYA22; AI426263; 2810418J22Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: CTD small phosphatase-like protein (Ctdspl); Recombinant Mouse CTD small phosphatase-like protein (Ctdspl); Ctdspl recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Positions: 1-276, Full length protein
• Sequence: MDGPAIITQVTNPKEDEARSPVAGEKASQRNISLKKQRGRSILSSFFCCFRDYNVEAPPANSPSVLPPLVEENGGLQKGDQRQVIPVPSPPAKYLLPEVTVLDYGKKCVVIDLDETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRELSKVIIVDNSPASYIFHPENAVPVQSWFDDMTDTELLDLIPFFEGLSREDDVYSMLHRLCSR
• Sequence Length: 276

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

NCBI and Uniprot Product Information

• NCBI GI #: 171460950
• NCBI GeneID: 69274
• NCBI Accession #: NP_598471.3
• NCBI GenBank Nucleotide #: NM_133710.3
• UniProt Accession #: P58465; Q52KL5
• Molecular Weight: 31,156 Da
• NCBI Official Full Name: CTD small phosphatase-like protein
• NCBI Official Synonym Full Names: CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
• NCBI Official Symbol: Ctdspl
• NCBI Official Synonym Symbols: SCP3; HYA22; AI426263; 2810418J22Rik
• NCBI Protein Information: CTD small phosphatase-like protein
• UniProt Protein Name: CTD small phosphatase-like protein
• Protein Family: CTD small phosphatase-like protein
• UniProt Gene Name: Ctdspl
• UniProt Synonym Gene Names: Nif1; Nifl; CTDSP-like; NLI-interacting factor 1; SCP3; Small CTD phosphatase 3

Uniprot Description

Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells ().