Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 ELISA Kit | CTDSP1 elisa kit
Mouse Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 (CTDSP1) ELISA Kit
Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.
Inter-assay Precision (Precision between assays)
Three samples of known concentration were tested in forty separate assays to assess inter-assay precision.
CV (%) = SD/meanX100
Intra-Assay: CV
Inter-Assay: CV
NCBI and Uniprot Product Information
Uniprot Description
CTDSP1: Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residues repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 3.1.3.16; Protein phosphatase, Ser/Thr (non-receptor)
Chromosomal Location of Human Ortholog: 1|1 C3
Cellular Component: extracellular exosome; nucleoplasm; nucleus
Molecular Function: CTD phosphatase activity; hydrolase activity; metal ion binding; phosphoprotein phosphatase activity; phosphoric monoester hydrolase activity; protein binding
Biological Process: negative regulation of G1/S transition of mitotic cell cycle; negative regulation of neurogenesis; negative regulation of neuron differentiation; negative regulation of protein phosphorylation; protein amino acid dephosphorylation; regulation of transcription from RNA polymerase II promoter
Research Articles on CTDSP1
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Product Notes
The Mouse CTDSP1 ctdsp1 (Catalog #AAA282293) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA282293 ELISA Kit recognizes Mouse CTDSP1. It is sometimes possible for the material contained within the vial of "Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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