Guinea Pig CTD Phosphatase 1 ELISA Kit | CTDP1 elisa kit
Guinea pig CTD Phosphatase 1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
Uniprot Description
CTDP1: a phospho-serine/threonine protein phosphatase which interacts with the carboxy-terminus of transcription initiation factor TFIIF-alpha, a transcription factor which regulates elongation as well as initiation by RNA polymerase II. Its phosphorylation increases binding to TFIIF-alpha, affecting transcription elongation. Alternative splicing results in two different isoforms.
Protein type: Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16; Motility/polarity/chemotaxis; Transcription initiation complex
Chromosomal Location of Human Ortholog: 18q23
Cellular Component: nucleoplasm; spindle pole; centrosome; cytoplasm; spindle; midbody; spindle midzone; actin cytoskeleton
Molecular Function: DNA-directed RNA polymerase activity; CTD phosphatase activity
Biological Process: transcription from RNA polymerase II promoter; viral reproduction; cell division; positive regulation of viral transcription; RNA elongation from RNA polymerase II promoter; gene expression; protein amino acid dephosphorylation; exit from mitosis
Disease: Congenital Cataracts, Facial Dysmorphism, And Neuropathy
Research Articles on CTDP1
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Product Notes
The Guinea Pig CTDP1 ctdp1 (Catalog #AAA728246) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA728246 ELISA Kit recognizes Guinea Pig CTDP1. It is sometimes possible for the material contained within the vial of "CTD Phosphatase 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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