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Cytochrome C Oxidase Subunit VIc Recombinant Protein | COX6c recombinant protein

Recombinant Cytochrome C Oxidase Subunit VIc (COX6c)

Reactivity
Human
Applications
ELISA, Immunoprecipitation, SDS-Page, Western Blot
Purity
> 90%
Synonyms
Cytochrome C Oxidase Subunit VIc; Recombinant Cytochrome C Oxidase Subunit VIc (COX6c); COX6c recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Source: Prokaryotic expression
Reactivity
Human
Purity/Purification
> 90%
Form/Format
Freeze-dried powder
Sequence Length
75
Applicable Applications for COX6c recombinant protein
SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP)
Usage
Reconstitute in PBS or others.
Endotoxin Level
< 1.0EU per 1ug (determined by the LAL method)
Buffer Formulation
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Fragment
Met1~Lys75
Tag
Two N-terminal Tags, His-tag and GST-tag
Residues & Tags
Met1~Lys75 with N-terminal His Tag
Subcellular Location
Secreted
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
Predicted: 38.8kDa
NCBI Official Full Name
cytochrome c oxidase subunit VIc preprotein
NCBI Official Synonym Full Names
cytochrome c oxidase subunit 6C
NCBI Official Symbol
COX6C
NCBI Protein Information
cytochrome c oxidase subunit 6C
UniProt Protein Name
Cytochrome c oxidase subunit 6C
Protein Family
UniProt Gene Name
COX6C
UniProt Entry Name
COX6C_HUMAN

NCBI Description

Cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes subunit VIc, which has 77% amino acid sequence identity with mouse subunit VIc. This gene is up-regulated in prostate cancer cells. A pseudogene has been found on chromosomes 16p12. [provided by RefSeq, Jul 2010]

Uniprot Description

COX6C: This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. Belongs to the cytochrome c oxidase subunit 6c family.

Protein type: EC 1.9.3.1; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation; Oxidoreductase; Mitochondrial

Chromosomal Location of Human Ortholog: 8q22.2

Cellular Component: mitochondrial inner membrane; mitochondrion

Biological Process: generation of precursor metabolites and energy; mitochondrial electron transport, cytochrome c to oxygen

Research Articles on COX6c

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Product Notes

The COX6c cox6c (Catalog #AAA2034533) is a Recombinant Protein produced from E Coli Source: Prokaryotic expression and is intended for research purposes only. The product is available for immediate purchase. The Recombinant Cytochrome C Oxidase Subunit VIc (COX6c) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Cytochrome C Oxidase Subunit VIc can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE; Western Blot (WB); ELISA (EIA); Immunoprecipitation (IP). Researchers should empirically determine the suitability of the COX6c cox6c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cytochrome C Oxidase Subunit VIc, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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