EFNB2 blocking peptide
EFNB2 Immunizing Peptide
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ephrin (EPH) family. The ephrins and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. This gene encodes an EFNB class ephrin which binds to the EPHB4 and EPHA3 receptors. [provided by RefSeq, Jul 2008]
Uniprot Description
EFNB2: a type I membrane protein of the ephrin family. A ligand of Eph-related receptor tyrosine kinases EphA3 and EphB4. Ephrins and ephrin receptors mediate numerous developmental processes, particularly in the nervous system. Ephrin-B2 is implicated in mediating developmental events, especially in the nervous system and in erythropoiesis. May play a role in constraining the orientation of longitudinally projecting axons
Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinase
Chromosomal Location of Human Ortholog: 13q33
Cellular Component: focal adhesion; integral to plasma membrane; plasma membrane
Molecular Function: ephrin receptor binding; protein binding; viral receptor activity
Biological Process: anatomical structure morphogenesis; axon guidance; cell adhesion; cell migration during sprouting angiogenesis; cell-cell signaling; entry of virus into host cell; ephrin receptor signaling pathway; lymph vessel development; organ morphogenesis; regulation of chemotaxis; T cell costimulation
Research Articles on EFNB2
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Product Notes
The EFNB2 efnb2 (Catalog #AAA427382) is a Blocking Peptide and is intended for research purposes only. The product is available for immediate purchase. The EFNB2 Immunizing Peptide reacts with Human, Mouse, Rat, Dog, Cow, Pig and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: CPKVDSKTVG QYE. It is sometimes possible for the material contained within the vial of "EFNB2, Blocking Peptide" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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